Science 1967 Apr 21;1563773:400-1. doi: 10.1126/science.156.3773.400.

Malic dehydrogenase isozymes: distribution in developing nucleate and anucleate halves of sea urchin eggs.

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Nucleate and anucleate halves of sea urchin eggs have seven and five forms of L-malic dehydrogenase, respectively. Fertilization results in reduction of the number of enzyme forms in both halves. The normal complement of seven isozymes in unfertilized eggs appears to be a synthesis of five soluble and four particulate forms. Reduction in the number of isozymes after fertilization takes place principally in solutble forms and appears to be under cytoplasmic control.

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Genes referenced: LOC100887844 LOC587800