Ophthalmology 1987 Dec 01;9412:1605-9. doi: 10.1016/s0161-6420(87)33243-9.

Retinal vascular loss in idiopathic central serous chorioretinopathy with bullous retinal detachment.

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Three patients with idiopathic central serous chorioretinopathy (ICSC) and bullous retinal detachment (RD) were examined at least 2 years after the onset of the disease in one patient and over 10 years in the other two patients. There were large areas of retinal pigment epithelium (RPE) degeneration in each patient. Interestingly, there was loss of retinal vascular trees in the inferior peripheral retina where the subretinal fluid presumably persisted for a long time. In one patient, there was a retinal neovascularization with sea-fan formation along the border of the vascular loss. To the authors'' knowledge, this finding has not been described in the literature.

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Genes referenced: LOC100887844 LOC115925415 nsmce2