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Echinobase
ECB-ART-31662
Gene 1990 Dec 15;962:295-300. doi: 10.1016/0378-1119(90)90267-u.
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Sequence of a sea urchin hsp70 gene and its 5'' flanking region.

La Rosa M , Sconzo G , Giudice G , Roccheri MC , Di Carlo M .


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We report the nucleotide sequence of a 4470-bp fragment derived from a sea urchin genomic clone containing part of a heat-shock protein 70 (Hsp70)-encoding gene. This fragment, named hsp70 gene II, contains 1271 bp of the flanking region and 3299 bp of structural gene sequence interrupted by five introns and encoding the N-terminal 371 amino acids (aa) of the protein. The 5'' flanking region contains a putative TATA element, two CCAAT boxes, four heat-shock consensus sequence elements (hse) and one consensus sequence for binding of Sp1. Remarkable homologies were observed for deduced aa sequence and intron-exon organization between hsp70 gene II and rat hsc73 gene.

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Genes referenced: LOC100887844 LOC105439191 LOC115929188