ECB-ART-31113
DNA Seq
1992 Jan 01;32:127-9. doi: 10.3109/10425179209034008.
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The sea urchin erg homolog defines a highly conserved erg-specific domain.
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A genomic clone, isolated from a phage library prepared from the DNA of the sea urchin Lytechinus variegatus, was shown by sequence analysis to be a homolog of the ets family genes, ERG and Fli-1. It contains an open reading frame of which the coding region begins at a consensus 3'' splice site and extends for 173 amino acid residues. The first 84 amino acids are homologous with all members of the ets gene family, while the remainder of the sequence is only homologous with the human ERG and murine Fli-1 genes. This latter region, designated R, represents a highly conserved erg-specific domain.
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Genes referenced: erg LOC100887844 LOC591473