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ECB-ART-30538
Differentiation 1978 Aug 18;112:103-7. doi: 10.1111/j.1432-0436.1978.tb00974.x.
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Effect of 5-bromodeoxyuridine on differentiation. II. The effect of early BUdR treatment on gastrulation of sea urchin embryos.

Czihak G .


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BUdR treatment of early cleavage stages is more effective on gastrulation the earlier the drug is administered before the 16-cell stage. The distribution of percentages of embryos gastrulating is in good agreement with the theoretical calculated values presented in part I and permit the assumption that BUdR may act by preventing normal transcription at, or shortly after, the 16-cell stage.

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Genes referenced: LOC100887844 LOC115919910 LOC590297