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Echinobase
ECB-ART-41712
Gene Expr Patterns 2010 Jan 01;107-8:323-7. doi: 10.1016/j.gep.2010.07.003.
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Characterization and expression of a sea star otx ortholog (Protxβ1/2) in the larva of Patiriella regularis.

Elia L , Cisternas P , Byrne M .


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A transcript of otx from the sea star Patiriella regularis (Protxβ1/2) was characterized and its expression in early bipinnaria larvae was documented by whole mount in situ hybridization (WMISH). The nucleotide sequence exhibited 94% identity with Amotxβ1/2 from the closely related species Patiria miniata. Protxβ1/2 was expressed strongly in the developing archenteron in the future fore and mid-gut regions. This was followed by expression of Protxβ1/2 in the developing enterocoels, mesodermal derivatives. This suggests a role for Protx in endomesoderm development. In coelom development, Protxβ1/2 was first expressed in the left coelom. Subsequently expression was evident in the right coelom, but localization was never as strong as in the left coelom. This asymmetry in Protxβ1/2 expression in the coeloms was evident up to the stage when they started to extend posteriorly. These data indicate that Protxβ1/2 may have a role in coelom development, particularly in the left coelom, a definitive adult structure.

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Genes referenced: LOC100887844 otx2