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J Nat Prod 2016 Apr 22;794:923-8. doi: 10.1021/acs.jnatprod.5b01007.
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Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes.

Tsyganov DV , Krayushkin MM , Konyushkin LD , Strelenko YA , Semenova MN , Semenov VV .

Analogues of the bioactive natural alkoxynaphthalene pycnanthulignene D were synthesized by an efficient method. The starting plant allylalkoxybenzenes (1) are easily available from the plant essential oils of sassafras, dill, and parsley. The target 1-arylalkoxynaphthalenes (5) exhibited antiproliferative activity in a phenotypic sea urchin embryo assay.

PubMed ID: 26910798
Article link: J Nat Prod

Genes referenced: LOC100887844