Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-32377
Proc Natl Acad Sci U S A 1987 May 01;849:2771-5. doi: 10.1073/pnas.84.9.2771.
Show Gene links Show Anatomy links

Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles.

Leslie RJ , Hird RB , Wilson L , McIntosh JR , Scholey JM .


???displayArticle.abstract???
Sea urchin embryos in second division have been lysed into microtubule-stabilizing buffers to yield mitotic cytoskeletons (MCSs) that consist of two mitotic spindles surrounded by a cortical array of filaments. Microtubules have been completely extracted from MCSs by incubation at 0 degrees C with Ca2+-containing buffer. An antibody to the microtubule translocator kinesin stains the spindles in MCSs and in MCSs treated with 5 mM ATP and also stains spindle-remnants of the MCSs after the microtubules have been extracted. We conclude that kinesin binds to a nonmicrotubule component in the mitotic spindle. Based on these results, we present several models of kinesin function in the spindle.

???displayArticle.pubmedLink??? 3106977
???displayArticle.pmcLink??? PMC304740
???displayArticle.link??? Proc Natl Acad Sci U S A
???displayArticle.grants??? [+]

Genes referenced: LOC100887844
???displayArticle.antibodies??? tubb1 Ab1

References [+] :
Bajer, Role of phragmoplast filaments in cell-plate formation. 1966, Pubmed