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ECB-ART-41329
J Gen Physiol 1926 May 20;95:709-14. doi: 10.1085/jgp.9.5.709.
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THE EFFECT OF HYDROGEN ION CONCENTRATION ON SWELLING OF CELLS.

Lucke B , McCutcheon M .


Abstract
1. The effect of HCl, NaOH, CO(2), and NH(3) on the volume of unfertilized Arbacia eggs was tested over a wide range of pH values. 2. No swelling occurred, except in HCl solutions, and there not until after injury or death had occurred. 3. Whereas the volume of erythrocytes and of proteins such as gelatin is known to be dependent on the pH of the solution, such a relation does not exist in the case of living and uninjured cells, at least of the type tested.

PubMed ID: 19872285
PMC ID: PMC2140849
Article link: J Gen Physiol



References :
Warburg, Studies on Carbonic Acid Compounds and Hydrogen Ion Activities in Blood and Salt Solutions. A Contribution to the Theory of the Equation of Lawrence J. Henderson and K. A. Hasselbach: Introduction. 2006, Pubmed