ECB-ART-42687
Nat Prod Res
2014 Jan 01;284:213-20. doi: 10.1080/14786419.2012.751596.
Show Gene links
Show Anatomy links
Pseudocnoside A, a new cytotoxic and antiproliferative triterpene glycoside from the sea cucumber Pseudocnus dubiosus leoninus.
???displayArticle.abstract???
A new triterpene glycoside, pseudocnoside A (1), was isolated from the sea cucumber Pseudocnus dubiosus leoninus. The structure of the new compound was established on the basis of extensive NMR spectroscopic analysis ((1)H and (13)C NMR, (1)H,(1)H-COSY, HMBC, HSQC, TOCSY and NOESY), HR-ESI-MS data and chemical transformations. In addition, the cytotoxicity and antiproliferative activities of 1 and structurally related triterpene glycosides isolated from the sea cucumbers Psolus patagonicus and Hemioedema spectabilis were evaluated against cancer cell lines A-549 and HeLa.
???displayArticle.pubmedLink??? 23244698
???displayArticle.link??? Nat Prod Res
Genes referenced: LOC100887844 LOC100893907 LOC115919910