Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-48165
Ecotoxicology 2007 Feb 01;161:95-108. doi: 10.1007/s10646-006-0119-8.
Show Gene links Show Anatomy links

Endocrine disrupting compounds and echinoderms: new ecotoxicological sentinels for the marine ecosystem.

Sugni M , Mozzi D , Barbaglio A , Bonasoro F , Candia Carnevali MD .


???displayArticle.abstract???
Echinoderms are valuable test species in marine ecotoxicology and offer a wide range of biological processes appropriate for this approach. In spite of this potential, available data in literature are still rather limited, particularly with regard to the possible effects of endocrine disrupter compounds (EDCs). This review presents echinoderms as useful models for ecotoxicological tests and gives a brief overview of the most significant results obtained in recent years, particularly in the context of the COMPRENDO EU project. In this research project two different aspects of echinoderm physiology, plausibly regulated by humoral mechanisms, were investigated: reproductive biology and regenerative development. Selected EDCs suspected for their androgenic or antiandrogenic action were tested at low concentrations. The results obtained so far showed that different parameters such as regenerative growth, histological pattern, egg diameter and gonad maturation were affected by the exposure to the selected compounds. These results substantiate that reproductive and regenerative phenomena of echinoderms can be considered valuable alternative models for studies on EDCs and confirm that these compounds interfere with fundamental physiological processes, including growth, development and reproductive competence.

???displayArticle.pubmedLink??? 17253161
???displayArticle.link??? Ecotoxicology



References [+] :
Andersen, Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. 2002, Pubmed