Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Science 1990 Jun 01;2484959:1115-8. doi: 10.1126/science.2188366.
Show Gene links Show Anatomy links

Cell interactions in the sea urchin embryo studied by fluorescence photoablation.

Ettensohn CA .

In many organisms, interactions between cells play a critical role in the specification of cell fates. In the sea urchin embryo, primary mesenchyme cells (PMCs) regulate the developmental program of a subpopulation of secondary mesenchyme cells (SMCs). The timing of this cell interaction was analyzed by means of a fluorescence photoablation technique, which was used to specifically ablate PMCs at various stages of development. In addition, the PMCs were microinjected into PMC-depleted recipient embryos at different developmental stages and their effect on SMC fate was examined. The critical interaction between PMCs and SMCs was brief and took place late in gastrulation. Before that time, SMCs were insensitive to the suppressive signals transmitted by the PMCs.

PubMed ID: 2188366
Article link: Science
Grant support: [+]

Genes referenced: LOC100887844 LOC115919910
Antibodies: msp130 Ab6