ECB-ART-42512
Ontogenez
2012 Jan 01;433:212-6.
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[Expression of transmitter receptor genes in early development of sea urchin Paracentrotus lividus].
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Neurotransmitters (including serotonin and acetylcholine) perform a number of prenervous functions in early sea urchin development. To detect the particular receptor components involved in these processes, we carried out a database search and nucleotide sequences homologous to serotonin receptor type 4, and the alpha6- and alpha10-subunits of nicotinic acetylcholine receptor were found among EST-clones from early Paracentrotus lividus embryos. Expression of these transcripts during early development was demonstrated using RT-PCR. These results are the first molecular biology evidence ofserotonin and acetylcholine receptor expression in sea urchin early embryogenesis.
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Genes referenced: LOC100887844 LOC100888622 LOC100891068 LOC576539