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Neurochem Res
1981 Jan 01;61:55-68. doi: 10.1007/bf00963906.
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Possible role of "prenervous" neurotransmitters in cellular interactions of early embryogenesis: a hypothesis.
Buznikov GA
,
Shmukler YB
.
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Evidence is presented in support of the working hypothesis that "prenervous" neurotransmitters directly participate in cell-cell interactions occurring during the first several cleavage divisions of sea urchin embryos, a function which may occur during the early development of higher animals as well. This intercellular signaling could be a link in the evolutionary progression from the use of these substances as intracellular regulators to their participation in cell-cell interactions occurring during synaptic transmission.
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