Li YX et al. (2013), Triterpenoids of marine origin as anti-cancer a...

ECB-ART-42954

Molecules 2013 Jul 04;187:7886-909. doi: 10.3390/molecules18077886.

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Triterpenoids of marine origin as anti-cancer agents.

Li YX , Himaya SW , Kim SK .

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Triterpenoids are the most abundant secondary metabolites present in marine organisms, such as marine sponges, sea cucumbers, marine algae and marine-derived fungi. A large number of triterpenoids are known to exhibit cytotoxicity against a variety of tumor cells, as well as anticancer efficacy in preclinical animal models. In this review efforts have been taken to review the structural features and the potential use of triterpenoids of marine origin to be used in the pharmaceutical industry as potential anti-cancer drug leads.

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Genes referenced: LOC100887844 LOC115925415

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	Figure 1. Isomalabaricane-type triterpenoids stellettins from marine sponge.
	Figure 2. Triterpenoid stelliferins from marine sponges.
	Figure 3. Triterpenoid geoditins from marine sponges.
	Figure 4. Triterpenoid sodwanones from marine sponges.
	Figure 5. Triterpenoid raspacionins from marine sponges.
	Figure 6. Triterpenoid sipholenols, sipholenones and siphonellinols from marine sponges.
	Figure 7. Triterpenoidglycosides fuscocinerosides, pervicoside C and holothurin Afrom sea cucumbers.
	Figure 8. Triterpenoid glycosides holothurin A3 and A4 from sea cucumbers.
	Figure 9. Triterpenoid glycosides arguside A, B and C from sea cucumbers.
	Figure 10. Triterpenoid glycosides arguside D and E from sea cucumbers.
	Figure 11. Triterpenoidglycosides impatienside A, bivittoside D, 17-dehydroxyholothurinoside A and griseaside A from sea cucumbers.
	Figure 12. Triterpenoid glycoside hillaside C from sea cucumber.
	Figure 13. Triterpenoid glycosides intercedensides A, B, and C from sea cucumbers.
	Figure 14. Triterpenoid glycosides philinopside E and intercedenside B from sea cucumbers.
	Figure 15. Triterpenoid glycosides philinopsides A and B from sea cucumbers.
	Figure 16. Triterpenoid glycosides frondoside A, cucumarioside A2-2 from sea cucumbers.
	Figure 17. Triterpenoid glycosides echinoside A and ds-echinoside A from sea cucumbers.
	Figure 18. Squalenoid-derived triterpenoids from marine algae.
	Figure 19. Cycloartane-type triterpenoids from marine algae.
	Figure 20. Triterpenoids xylariacins A-C from marine-derived fungi.