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Prog Mol Subcell Biol 2005 Jan 01;39:7-44. doi: 10.1007/3-540-27683-1_2.
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Cell adhesion and communication: a lesson from echinoderm embryos for the exploitation of new therapeutic tools.

Zito F , Costa C , Sciarrino S , Cavalcante C , Poma V , Matranga V .

In this chapter, we summarise fundamental findings concerning echinoderms as well as research interests on this phylum for biomedical and evolutionary studies. We discuss how current knowledge of echinoderm biology, in particular of the sea urchin system, can shed light on the understanding of important biological phenomena and in dissecting them at the molecular level. The general principles of sea urchin embryo development are summarised, mainly focusing on cell communication and interactions, with particular attention to the cell-extracellular matrix and cell-cell adhesion molecules and related proteins. Our purpose is not to review all the work done over the years in the field of cellular interaction in echinoderms. On the contrary, we will rather focus on a few arguments in an effort to re-examine some ideas and concepts, with the aim of promoting discussion in this rapidly growing field and opening new routes for research on innovative therapeutic tools.

PubMed ID: 17152692
Article link: Prog Mol Subcell Biol

Genes referenced: LOC100887844 LOC115919910