ECB-ART-40789
Chem Biodivers
2008 Jul 01;57:1425-33. doi: 10.1002/cbdv.200890131.
Show Gene links
Show Anatomy links
Argusides D and E, two new cytotoxic triterpene glycosides from the sea cucumber Bohadschia argus Jaeger.
???displayArticle.abstract???
Two new triterpene glycosides, argusides D and E (1 and 2, resp.), have been isolated from the sea cucumber Bohadschia argus Jaeger collected in the South China Sea. Their structures have been established by spectral analysis (ESI-MS, and 1D- and 2D-NMR) and chemical evidence. Compounds 1 and 2 both possess an holostane-type triterpene aglycone with a C(9)=C(11) bond, an OH group at C(12), and tetrasaccharide moieties, but differ in the side chains. The two glycosides exhibited significant cytotoxicities against four human tumor cell lines, A549, HCT-116, HepG2, and MCF-7.
???displayArticle.pubmedLink??? 18649309
???displayArticle.link??? Chem Biodivers
Genes referenced: LOC100887844 LOC100893907 LOC115919910