Dev Growth Differ 1983 Jan 01;253:227-237. doi: 10.1111/j.1440-169X.1983.00227.x.

Studies on Unequal Cleavage in Sea Urchins II. Surface Differentiation and the Direction of Nuclear Migration: (sea urchin micromere/cortical differentiation/equal-unequal cleavage).

Abstract
Cortical features of the meso- and macromeres differ from those of the micromeres in sea urchins. At the end of the 8-cell stage, the four animal cells have a continuous row of vesicles lining the free surface of the cell by transmission electron microscopy (TEM) and the nuclei and the resulting mitotic apparatuses (MA) remain at the cell centers and eventually divide equally into eight mesomeres. In the four vegetal cells, narrow gaps can be seen in the vesicular rows near the vegetal pole. The resting nuclei migrate to these gaps and on forming the spindles, they point directly to the gaps. The result is formation of vesicle-free micromeres and vesicle-covered macromeres by unequal divisions.

PubMed ID: 37281944
Article link: Dev Growth Differ