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Echinobase
ECB-ART-42552
Biochem Biophys Res Commun 2012 Aug 31;4253:595-8. doi: 10.1016/j.bbrc.2012.08.033.
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Structure of acrosome reaction-inducing substance in the jelly coat of starfish eggs: a mini review.

Hoshi M , Moriyama H , Matsumoto M .


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Our knowledge at present on the structure of acrosome-reaction inducing substance (ARIS) in the jelly coat of starfish eggs is summarized. ARIS ia a proteoglycan-like molecule consisting of very long, linear, and highly sulfated glycans and three ARIS proteins, ARIS1-3. Detailed structures of the major glycan of ARIS and of ARIS1-3 are discussed. 3D-models of ARIS glycans are also presented. Phylogenetic distribution of ARIS proteins and/or genes indicates that ARIS genes are well preserved from the Ctenophore to Cephalochordata. In the Echinodermata, ARIS1-3 and ARIS genes were detected in all classes except for sea urchins.

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Genes referenced: LOC100887844