Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Sci Rep
2017 May 16;71:1954. doi: 10.1038/s41598-017-02077-5.
Show Gene links
Show Anatomy links
Maternal antioxidant provisioning mitigates pollutant-induced oxidative damage in embryos of the temperate sea urchin Evechinus chloroticus.
Lister KN
,
Lamare MD
,
Burritt DJ
.
???displayArticle.abstract???
One mechanism of pollution resistance in marine populations is through transgenerational plasticity, whereby offspring capacity to resist pollution reflects parental exposure history. Our study aimed to establish correlations between oxidative stress biomarkers and key reproductive fitness parameters in the temperate sea urchin Evechinus chloroticus following exposure to dietary polycyclic aromatic hydrocarbons (PAHs). PAH-exposed adults exhibited total gonad tissue concentrations of PAHs in excess of 4 and 5 times baseline levels, for females and males respectively. Antioxidant enzymes were upregulated and oxidative lipid and protein damage to gonad tissues occurred. In addition, early stage offspring reflected maternal antioxidant status, with progeny derived from exposed females demonstrating significantly higher baselines than those derived from control females. Maternal exposure history enhanced the capacity of embryos to minimise oxidative damage to lipids and proteins following exposure to additional PAHs, but provided less of an advantage in protection against oxidative DNA damage. Abnormal embryonic development was largely independent of oxidative damage, remaining high in all embryo populations regardless of parental PAH-history. Overall, results document evidence for maternal transfer of antioxidant potential in E. chloroticus, but imply that a short-term inherited resilience against oxidative stress may not necessarily translate to a fitness or survival gain.
Figure 1. Parents can influence the ability of their progeny to respond to environmental stress through genetic and non-genetic pathways. Modified from ref. 4.
Figure 2. Mean ± SE activities of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx), glyoxalase-I (Glx-I), glyoxalase-II (Glx-II), glutathione-S-transferase (GST), total glutathione and percentage reduced glutathione (GSH), protein carbonyl, lipid hydroperoxide and 8-hydroxydeoxyguanosine in 3-day old Evechinus chloroticus embryos exposed to control (0 ng/L), low (540 ng/L) and high (1080 ng/L) PAH treatments. Embryos were derived from contaminant-naïve versus contaminant-experienced parents and combinations of both (e.g. NF * NM = naïve female crossed with naïve male). N = 3.
Almeida,
DNA and lipid damage in the brown mussel Perna perna from a contaminated site.
2003, Pubmed
Almeida,
DNA and lipid damage in the brown mussel Perna perna from a contaminated site.
2003,
Pubmed
Alonso-Alvarez,
An experimental manipulation of life-history trajectories and resistance to oxidative stress.
2006,
Pubmed
Alves de Almeida,
Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: antioxidants, lipid peroxidation and DNA damage.
2007,
Pubmed
Au,
Reproductive impairment of sea urchins upon chronic exposure to cadmium. Part I: Effects on gamete quality.
2001,
Pubmed
,
Echinobase
Au,
Reproductive impairment of sea urchin upon chronic exposure to cadmium. Part II: Effects on sperm development.
2001,
Pubmed
,
Echinobase
Bellas,
Toxicity of organic compounds to marine invertebrate embryos and larvae: a comparison between the sea urchin embryogenesis bioassay and alternative test species.
2005,
Pubmed
,
Echinobase
Bellas,
Ecotoxicological evaluation of polycyclic aromatic hydrocarbons using marine invertebrate embryo-larval bioassays.
2008,
Pubmed
,
Echinobase
Bize,
Fecundity and survival in relation to resistance to oxidative stress in a free-living bird.
2008,
Pubmed
Byrne,
Global change ecotoxicology: Identification of early life history bottlenecks in marine invertebrates, variable species responses and variable experimental approaches.
2012,
Pubmed
Castellano,
Shedding light on ovothiol biosynthesis in marine metazoans.
2016,
Pubmed
,
Echinobase
Cavalieri,
The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation.
1992,
Pubmed
Costantini,
Oxidative stress in ecology and evolution: lessons from avian studies.
2008,
Pubmed
Crean,
Adaptive paternal effects? Experimental evidence that the paternal environment affects offspring performance.
2013,
Pubmed
Donnelly,
Glutathione and hypotaurine in vitro: effects on human sperm motility, DNA integrity and production of reactive oxygen species.
2000,
Pubmed
Gilbert,
Ecological developmental biology: developmental biology meets the real world.
2001,
Pubmed
Hamdoun,
Embryo stability and vulnerability in an always changing world.
2007,
Pubmed
Hylland,
Polycyclic aromatic hydrocarbon (PAH) ecotoxicology in marine ecosystems.
2006,
Pubmed
Lesser,
Exposure to ultraviolet radiation causes apoptosis in developing sea urchin embryos.
2003,
Pubmed
,
Echinobase
Lesser,
Oxidative stress in marine environments: biochemistry and physiological ecology.
2006,
Pubmed
Lesser,
Depth-dependent effects of ultraviolet radiation on survivorship, oxidative stress and DNA damage in sea urchin (Strongylocentrotus droebachiensis) embryos from the Gulf of Maine.
2010,
Pubmed
,
Echinobase
Lister,
Sea ice protects the embryos of the Antarctic sea urchin Sterechinus neumayeri from oxidative damage due to naturally enhanced levels of UV-B radiation.
2010,
Pubmed
,
Echinobase
Lister,
Oxidative damage in response to natural levels of UV-B radiation in larvae of the tropical sea urchin Tripneustes gratilla.
2010,
Pubmed
,
Echinobase
Lister,
Dietary pollutants induce oxidative stress, altering maternal antioxidant provisioning and reproductive output in the temperate sea urchin Evechinus chloroticus.
2016,
Pubmed
,
Echinobase
Lister,
Pollutant resilience in embryos of the Antarctic sea urchin Sterechinus neumayeri reflects maternal antioxidant status.
2015,
Pubmed
,
Echinobase
Livingstone,
Contaminant-stimulated reactive oxygen species production and oxidative damage in aquatic organisms.
2001,
Pubmed
Marshall,
Transgenerational plasticity in the sea: context-dependent maternal effects across the life history.
2008,
Pubmed
Meitern,
On the methodological limitations of detecting oxidative stress: effects of paraquat on measures of oxidative status in greenfinches.
2013,
Pubmed
Metcalfe,
Does reproduction cause oxidative stress? An open question.
2013,
Pubmed
Monaghan,
Oxidative stress as a mediator of life history trade-offs: mechanisms, measurements and interpretation.
2009,
Pubmed
Munday,
Transgenerational acclimation of fishes to climate change and ocean acidification.
2014,
Pubmed
Pillai,
Polycyclic aromatic hydrocarbons disrupt axial development in sea urchin embryos through a beta-catenin dependent pathway.
2003,
Pubmed
,
Echinobase
Regoli,
Oxidative pathways of chemical toxicity and oxidative stress biomarkers in marine organisms.
2014,
Pubmed
Schäfer,
Gonadal lesions of female sea urchin (Psammechinus miliaris) after exposure to the polycyclic aromatic hydrocarbon phenanthrene.
2009,
Pubmed
,
Echinobase
Schäfer,
Sex-specific biochemical and histological differences in gonads of sea urchins (Psammechinus miliaris) and their response to phenanthrene exposure.
2011,
Pubmed
,
Echinobase
Sewell,
Ocean acidification and fertilization in the antarctic sea urchin Sterechinus neumayeri: the importance of polyspermy.
2014,
Pubmed
,
Echinobase
Tarry-Adkins,
Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats.
2008,
Pubmed
Valavanidis,
Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants.
2006,
Pubmed
den Besten,
Cytochrome P450 monooxygenase system in echinoderms.
1998,
Pubmed
,
Echinobase