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ECB-ART-52882
J Asian Nat Prod Res 2024 Feb 09;:1-10. doi: 10.1080/10286020.2024.2311140.
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New polyketides from the starfish-derived symbiotic fungus Penicillium sp. GGF16-1-2.

He YP , Xiang J , Shao XH , Feng C , Zhang Q , Wang YM , Zhang CX .


Abstract
One new rare carbon-bridged citrinin dimer quinocitrindimer C (1) as a pair of epimers, two new polyketide penicilliodes D (3) and E (4) together with nine known citrinin derivatives, were isolated from the fermentation broth of starfish-derived symbiotic fungus Penicillium sp. GGF16-1-2. Their structures and configurations were elucidated by comprehensively spectroscopic data analysis and electronic circular dichroism calculations. Eleven citrinin derivatives were tested by Colletotrichum gloeosporioides, and compound 2 played a significant antifungal activity against Colletotrichum gloeosporioides with LC50 value of 0.27 μg/ml.

PubMed ID: 38334077
Article link: J Asian Nat Prod Res