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ECB-ART-37543
J Nat Prod 2000 Aug 01;638:1178-81. doi: 10.1021/np000030f.
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Hemolytic polar steroidal constituents of the starfish Aphelasterias japonica.

Ivanchina NV , Kicha AA , Kalinovsky AI , Dmitrenok PS , Stonik VA , Riguera R , Jiménez C .


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A reinvestigation of the polar steroid fraction from the starfish Aphelasterias japonica, collected near the Russian shore of the Sea of Japan, has afforded two new compounds, the disulfated quinovoside aphelasteroside C (1) and the monosulfated polyhydroxysteroid aphelaketotriol (2). Compounds 1 and 2 contain a unique 23-oxo-24-hydroxylated side chain that is unprecedented in marine steroids. The known compounds cheliferoside L1 (3), 3-O-sulfoasterone (4), forbeside E3 (5), and 3-O-sulfothornasterol A (6) were also isolated from this source. Compounds 1-3, 5, and 6 showed hemolytic activity to mouse erythrocytes.

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Genes referenced: LOC100887844 LOC593824