Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-37420
J Hered 2000 Jan 01;912:146-9. doi: 10.1093/jhered/91.2.146.
Show Gene links Show Anatomy links

Heteroplasmy of mitochondrial DNA in the ophiuroid Astrobrachion constrictum.

Steel DJ , Trewick SA , Wallis GP .


???displayArticle.abstract???
We demonstrate the presence of mitochondrial heteroplasmy for the cytochrome oxidase I (COI) gene of the brittle star (Astrobrachion constrictum). One of the 117 individuals analyzed contained two distinct single-strand conformation polymorphism (SSCP) haplotypes differing by two substitutions; another showed sequence evidence for heteroplasmy. We used polymerase chain reaction (PCR) cloning, SSCP, and sequencing of a 480 bp region of the 5'' end of COI to isolate and characterize these haplotypes. This is the first properly substantiated case of heteroplasmy in an echinoderm species and may have arisen from paternal leakage.

???displayArticle.pubmedLink??? 10768129
???displayArticle.link??? J Hered


Genes referenced: polr3a