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Echinobase
ECB-ART-32538
J Antibiot (Tokyo) 1988 Mar 01;413:296-301. doi: 10.7164/antibiotics.41.296.
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A new immunomodulator, FR-900483.

Shibata T , Nakayama O , Tsurumi Y , Okuhara M , Terano H , Kohsaka M .


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FR-900483 is a new immunoactive substance produced by a fungus, Nectria lucida F-4490. Concanavalin A-stimulated lymphocyte proliferation, which had been suppressed by addition of immunosuppressive factor, was restored to a normal level by the addition of FR-900483. Furthermore, FR-900483 restored the capacity of immunosuppressed mice to produce antibody against sheep red blood cells.

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???displayArticle.link??? J Antibiot (Tokyo)