Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-50764
Nature 2015 Apr 23;5207548:456-65. doi: 10.1038/nature14434.
Show Gene links Show Anatomy links

The deuterostome context of chordate origins.

Lowe CJ , Clarke DN , Medeiros DM , Rokhsar DS , Gerhart J .


Abstract
Our understanding of vertebrate origins is powerfully informed by comparative morphology, embryology and genomics of chordates, hemichordates and echinoderms, which together make up the deuterostome clade. Striking body-plan differences among these phyla have historically hindered the identification of ancestral morphological features, but recent progress in molecular genetics and embryology has revealed deep similarities in body-axis formation and organization across deuterostomes, at stages before morphological differences develop. These developmental genetic features, along with robust support of pharyngeal gill slits as a shared deuterostome character, provide the foundation for the emergence of chordates.

PubMed ID: 25903627
Article link: Nature
Grant support: [+]


References [+] :
Abedin, The premetazoan ancestry of cadherins. 2008, Pubmed