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J Cell Biol
1971 Jun 01;493:692-701. doi: 10.1083/jcb.49.3.692.
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The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos.
Hogan B
,
Gross PR
.
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Emetine is a potent inhibitor of protein synthesis in sea urchin embryos. At a concentration of the drug that rapidly inhibits protein synthesis in blastulae by 95%, uridine incorporation into RNA continues for more than 1 hr and presumptive histone messenger RNA is synthesized and transported into the cytoplasm where it is apparently associated with polyribosomes. Possible explanations of this result and its implications for the "informasome" theory of messenger transport in embryonic cells are discussed.
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Mechanism of cycloheximide inhibition of protein synthesis in a cell-free system prepared from rat liver.
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Baliga,
Mechanism of cycloheximide inhibition of protein synthesis in a cell-free system prepared from rat liver.
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FAN,
MESSENGER RNA DECAY AND PROTECTION.
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BASE COMPOSITION OF RNA SYNTHESIZED DURING CLEAVAGE OF THE SEA URCHIN EMBRYO.
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,
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Girard,
The effect of HeLa cell cytoplasm on the rate of sedimentation of RNA.
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Synthesis of ribosomal RNA during sea urchin development. II. Electrophoretic analysis of nuclear and cytoplasmic RNA's.
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,
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Grollman,
Inhibitors of protein biosynthesis. V. Effects of emetine on protein and nucleic acid biosynthesis in HeLa cells.
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Grollman,
Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics.
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Hoerz,
Evidence for a proposed initiation complex for protein synthesis in reticulocyte polyribosome profiles.
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Hunt,
Control of haemoglobin synthesis: rate of translation of the messenger RNA for the alpha and beta chains.
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Hynes,
A method for separating cells from early sea urchin embryos.
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,
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Kedes,
Identification in cleaving embryos of three RNA species serving as templates for the synthesis of nuclear proteins.
1969,
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Kedes,
Synthesis and function of messenger RNA during early embryonic development.
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Kedes,
Synthesis of nuclear and chromosomal proteins on light polyribosomes during cleavage in the sea urchin embryo.
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,
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Kijima,
Rate of nuclear ribonucleic acid turnover in sea urchin embryos.
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,
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Latham,
Entrance of mRNA into HeLa cell cytoplasm in puromycin-treated cells.
1965,
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Lin,
The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system.
1966,
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McKeehan,
The mechanism of cycloheximide inhibition of protein synthesis in rabbit reticulocytes.
1969,
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Penman,
Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells.
1968,
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Sconzo,
Synthesis of ribosomal RNA during sea urchin development. 3. Evidence for an activation of transcription.
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,
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Spirin,
The second Sir Hans Krebs Lecture. Informosomes.
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Warner,
Ribosome formation in HeLa cells in the absence of protein synthesis.
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Willems,
The regulation of RNA synthesis and processing in the nucleolus during inhibition of protein synthesis.
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Synthesis of protein for DNA replication and cleavage events in the sand dollar embryo.
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,
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