Tsuzuki T , Takano S , Sakaguchi N , Kudoh T , Murayama T , Sakurai T , Hashii M , Higashida H , Weber K , Guse AH , Kameda T , Hirokawa T , Kumaki Y , Arisawa M , Potter BV , Shuto S .

101010 Wellcome Trust

Amina, Intracellular calcium elevation induced by extracellular application of cyclic-ADP-ribose or oxytocin is temperature-sensitive in rodent NG108-15 neuronal cells with or without exogenous expression of human oxytocin receptors. 2010, Pubmed

Amina, Intracellular calcium elevation induced by extracellular application of cyclic-ADP-ribose or oxytocin is temperature-sensitive in rodent NG108-15 neuronal cells with or without exogenous expression of human oxytocin receptors. 2010, Pubmed
Bellon, 4'-Thio-oligo-beta-D-ribonucleotides: synthesis of beta-4'-thio-oligouridylates, nuclease resistance, base pairing properties, and interaction with HIV-1 reverse transcriptase. 1993, Pubmed
Bobek, Preparation and activity of the 4'-thio derivatives of some 6-substituted purine nucleosides. 1970, Pubmed
Clapper, Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphate. 1987, Pubmed , Echinobase
Dyson, The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogues. 1991, Pubmed
Fukuoka, An efficient synthesis of cyclic IDP- and cyclic 8-bromo-IDP-carbocyclic-riboses using a modified Hata condensation method to form an intramolecular pyrophosphate linkage as a key step. An entry to a general method for the chemical synthesis of cyclic ADP-ribose analogues. 2000, Pubmed
Galione, Cyclic ADP-ribose and the regulation of calcium-induced calcium release in eggs and cardiac myocytes. 1998, Pubmed , Echinobase
Galione, Cyclic ADP-ribose: a new way to control calcium. 1993, Pubmed , Echinobase
Ganellin, The pressor activity of burimamide: a relationship between chemical constitution and pressor activity of burimamide and related histamine H2-receptor antagonists. 1977, Pubmed
Graham, NMR solution structure and conformational analysis of the calcium release agent cyclic adenosine 5'-diphosphate ribose (cADPR). 2001, Pubmed
Graham, cADPR analogues: effect of an adenosine 2'- or 3'-methoxy group on conformation. 2004, Pubmed
Gu, Synthesis and biological evaluation of novel membrane-permeant cyclic ADP-ribose mimics: N1-[(5''-O-phosphorylethoxy)methyl]-5'-O-phosphorylinosine 5',5''-cyclicpyrophosphate (cIDPRE) and 8-substituted derivatives. 2004, Pubmed
Guse, Intracellular Ca2+ pools in Jurkat T-lymphocytes. 1993, Pubmed
Guse, Regulation of calcium signaling by the second messenger cyclic adenosine diphosphoribose (cADPR). 2004, Pubmed
Guse, Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activity. 2002, Pubmed
Guse, Biochemistry, biology, and pharmacology of cyclic adenosine diphosphoribose (cADPR). 2004, Pubmed
Guse, Ca2+ entry induced by cyclic ADP-ribose in intact T-lymphocytes. 1997, Pubmed
Guse, Cyclic ADP-ribose: a novel Ca2+-mobilising second messenger. 1999, Pubmed , Echinobase
Hashii, Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells. 2005, Pubmed
Higashida, Selective coupling of different muscarinic acetylcholine receptors to neuronal calcium currents in DNA-transfected cells. 1990, Pubmed
Higashida, Cyclic ADP-ribose as a second messenger revisited from a new aspect of signal transduction from receptors to ADP-ribosyl cyclase. 2001, Pubmed
Huang, Syntheses and calcium-mobilizing evaluations of N1-glycosyl-substituted stable mimics of cyclic ADP-ribose. 2002, Pubmed
Jeong, Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-uronamides as highly potent and selective agonists at the human A3 adenosine receptor. 2006, Pubmed
Jin, CD38 is critical for social behaviour by regulating oxytocin secretion. 2007, Pubmed
Kim, Position of cyclization in cyclic ADP-ribose. 1993, Pubmed
Kudoh, Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety. 2005, Pubmed , Echinobase
Lee, Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity. 1989, Pubmed , Echinobase
Lee, Calcium mobilization by dual receptors during fertilization of sea urchin eggs. 1993, Pubmed , Echinobase
Lee, Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization. 2012, Pubmed
Lee, The crystal structure of cyclic ADP-ribose. 1994, Pubmed
Lee, Wide distribution of an enzyme that catalyzes the hydrolysis of cyclic ADP-ribose. 1993, Pubmed , Echinobase
Lee, Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP. 1997, Pubmed , Echinobase
Liu, Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. 2006, Pubmed
Moreau, Structural determinants for N1/N7 cyclization of nicotinamide hypoxanthine 5'-dinucleotide (NHD+) derivatives by ADP-ribosyl cyclase from aplysia californica: Ca2+-mobilizing activity of 8-substituted cyclic inosine 5'-diphosphoribose analogues in T-lymphocytes. 2006, Pubmed
Moreau, Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells. 2012, Pubmed
Potter, Medicinal chemistry and pharmacology of cyclic ADP-ribose. 2004, Pubmed
Schwarzmann, Knock-down of the type 3 ryanodine receptor impairs sustained Ca2+ signaling via the T cell receptor/CD3 complex. 2002, Pubmed
Shiwa, Molecular cloning and characterization of ryanodine receptor from unfertilized sea urchin eggs. 2002, Pubmed , Echinobase
Shuto, Convergent synthesis and unexpected Ca(2+)-mobilizing activity of 8-substituted analogues of cyclic ADP-carbocyclic-ribose, a stable mimic of the Ca(2+)-mobilizing second messenger cyclic ADP-ribose. 2003, Pubmed , Echinobase
Shuto, Total synthesis of cyclic ADP-carbocyclic-ribose, a stable mimic of Ca2+-mobilizing second messenger cyclic ADP-ribose. 2001, Pubmed , Echinobase
Shuto, Chemistry of cyclic ADP-ribose and its analogs. 2004, Pubmed
Swarbrick, Total synthesis of a cyclic adenosine 5'-diphosphate ribose receptor agonist. 2012, Pubmed
Takahashi, Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability. 2009, Pubmed
Toyohara, Pharmacokinetics and metabolism of 5-125I-iodo-4'-thio-2'-deoxyuridine in rodents. 2003, Pubmed
Tsuzuki, Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger. 2014, Pubmed
Venturi, From eggs to hearts: what is the link between cyclic ADP-ribose and ryanodine receptors? 2012, Pubmed , Echinobase
Wagner, First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADPR agonist. 2004, Pubmed
Wagner, Rapid synthetic route toward structurally modified derivatives of cyclic adenosine 5'-diphosphate ribose. 2005, Pubmed
Walseth, Synthesis and characterization of antagonists of cyclic-ADP-ribose-induced Ca2+ release. 1993, Pubmed , Echinobase
Wang, Automatic atom type and bond type perception in molecular mechanical calculations. 2006, Pubmed
Wang, Development and testing of a general amber force field. 2004, Pubmed
Xu, Synthesis and agonist activity of cyclic ADP-ribose analogues with substitution of the northern ribose by ether or alkane chains. 2006, Pubmed
Yoshimura, A facile, alternative synthesis of 4'-thioarabinonucleosides and their biological activities. 1997, Pubmed
Yu, A novel fluorescent cell membrane-permeable caged cyclic ADP-ribose analogue. 2012, Pubmed
Zhang, Vascular physiology of a Ca2+ mobilizing second messenger - cyclic ADP-ribose. 2006, Pubmed
Zhang, Bioorganic chemistry of cyclic ADP-ribose (cADPR). 1999, Pubmed , Echinobase