Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Acta Histochem
2007 Jan 01;1094:338-42. doi: 10.1016/j.acthis.2007.02.004.
Show Gene links
Show Anatomy links
Cyclodextrin, a probe for studying adhesive interactions.
Sajadi S
,
Rojas P
,
Oppenheimer SB
.
???displayArticle.abstract???
In this short communication, we introduce alpha-cyclodextrin as a new probe to study mechanisms of adhesive interactions. We show that this cyclic polysaccharide, that consisting of six glucosyl residues linked by alpha-1,4 bonds, was the only sugar of 22 tested that dramatically blocked a specific cellular interaction in the sea urchin embryo (p<0.001 compared with non-sugar controls). A total of 150-400 embryos were sampled for each concentration of each sugar tested. Mechanisms of cellular interactions have been studied for almost a century and they still remain poorly understood. Cyclodextrin is an exciting new tool that can be utilized for investigating these mechanisms.
Akasaka,
Scanning electron microscopical study of the inside of sea urchin embryos (Pseudocentotus depressus). Effects of Aryl beta-xyloside, tunicamycin and deprivation of sulfate tions.
1980, Pubmed,
Echinobase
Akasaka,
Scanning electron microscopical study of the inside of sea urchin embryos (Pseudocentotus depressus). Effects of Aryl beta-xyloside, tunicamycin and deprivation of sulfate tions.
1980,
Pubmed
,
Echinobase
Blackburn,
Carbohydrate-specific cell adhesion is mediated by immobilized glycolipids.
1983,
Pubmed
Camby,
Galectin-1: a small protein with major functions.
2006,
Pubmed
Davidson,
The sea urchin genome: where will it lead us?
2006,
Pubmed
,
Echinobase
Guarnaccia,
Tunicamycin inhibits ganglioside biosynthesis in neuronal cells.
1983,
Pubmed
Heifetz,
Biosynthesis of N-glycosidically linked glycoproteins during gastrulation of sea urchin embryos.
1979,
Pubmed
,
Echinobase
Khurrum,
Carbohydrate involvement in cellular interactions in sea urchin gastrulation.
2004,
Pubmed
,
Echinobase
Kinoshita,
The role of proteoglycan in the development of sea urchins. I. Abnormal development of sea urchin embryos caused by the disturbance of proteoglycan synthesis.
1979,
Pubmed
,
Echinobase
Latham,
Accessing the embryo interior without microinjection.
1998,
Pubmed
,
Echinobase
Latham,
A putative role for carbohydrates in sea urchin gastrulation.
1999,
Pubmed
,
Echinobase
Schneider,
The effect of tunicamycin, an inhibitor of protein glycosylation, on embryonic development in the sea urchin.
1978,
Pubmed
,
Echinobase
Sodergren,
The genome of the sea urchin Strongylocentrotus purpuratus.
2006,
Pubmed
,
Echinobase
Whittaker,
The echinoderm adhesome.
2006,
Pubmed
,
Echinobase