Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
ACS Omega
2023 Oct 03;839:35791-35799. doi: 10.1021/acsomega.3c03299.
Show Gene links
Show Anatomy links
Physicochemical and Biochemical Characterization of Collagen from Stichopus cf. horrens Tissues for Use as Stimuli-Responsive Thin Films.
Sisican KMD
,
Torreno VPM
,
Yu ET
,
Conato MT
.
Abstract
The mutable collagenous tissue (MCT) of sea cucumber, with its ability to rapidly change its stiffness and extensibility in response to different environmental stress conditions, serves as inspiration for the design of new smart functional biomaterials. Collagen, extracted from the body wall of Stichopus cf. horrens, a species commonly found in the Philippines, was characterized for its suitability as stimuli-responsive films. Protein BLAST search showed the presence of sequences commonly found in type VII and IX collagen, suggesting that Stichopus horrens collagen is heterotypic. The maximum transition temperature recorded was 56.0 ± 2 °C, which is higher than those of other known sources of marine collagen. This suggests that S. horrens collagen has better thermal stability and durability. Collagen-based thin films were then prepared, and atomic force microscopy (AFM) imaging showed the visible collagen network comprising the films. The thin films were subjected to thermomechanical analysis with degradation starting at >175 °C. At 100-150 °C, the collagen-based films apparently lose their translucency due to the removal of moisture. Upon exposure to ambient temperature, instead of degrading, the films were able to revert to the original state due to the readsorption of moisture. This study is a demonstration of a smart biomaterial developed from S. cf. horrens collagen with potential applications in food, pharmaceutical, biomedical, and other collagen-based research.
Adibzadeh,
Purification and characterization of pepsin-solubilized collagen from skin of sea cucumber Holothuria parva.
2014, Pubmed,
Echinobase
Adibzadeh,
Purification and characterization of pepsin-solubilized collagen from skin of sea cucumber Holothuria parva.
2014,
Pubmed
,
Echinobase
Ahmed,
Characterization of marine derived collagen extracted from the by-products of bigeye tuna (Thunnus obesus).
2019,
Pubmed
Bordbar,
High-value components and bioactives from sea cucumbers for functional foods--a review.
2011,
Pubmed
,
Echinobase
Bornstein,
Structurally distinct collagen types.
1980,
Pubmed
Coppola,
Marine Collagen from Alternative and Sustainable Sources: Extraction, Processing and Applications.
2020,
Pubmed
,
Echinobase
Eyre,
Collagen: molecular diversity in the body's protein scaffold.
1980,
Pubmed
Fassini,
Diverse and Productive Source of Biopolymer Inspiration: Marine Collagens.
2021,
Pubmed
Ferrario,
Marine-derived collagen biomaterials from echinoderm connective tissues.
2017,
Pubmed
,
Echinobase
Ganewatta,
Chemical syntheses of bioinspired and biomimetic polymers toward biobased materials.
2021,
Pubmed
Ge,
Comprehensive Assessment of Nile Tilapia Skin (Oreochromis niloticus) Collagen Hydrogels for Wound Dressings.
2020,
Pubmed
Goh,
Collagenous Extracellular Matrix Biomaterials for Tissue Engineering: Lessons from the Common Sea Urchin Tissue.
2017,
Pubmed
,
Echinobase
Liu,
Action of trypsin on structural changes of collagen fibres from sea cucumber (Stichopus japonicus).
2018,
Pubmed
,
Echinobase
Mo,
Interfibrillar stiffening of echinoderm mutable collagenous tissue demonstrated at the nanoscale.
2016,
Pubmed
,
Echinobase
Motokawa,
Dynamic mechanical properties of body-wall dermis in various mechanical states and their implications for the behavior of sea cucumbers.
2003,
Pubmed
,
Echinobase
Persikov,
Prediction of collagen stability from amino acid sequence.
2005,
Pubmed
Qin,
Unfolding/Refolding Study on Collagen from Sea Cucumber Based on 2D Fourier Transform Infrared Spectroscopy.
2016,
Pubmed
,
Echinobase
Rabotyagova,
Collagen Structural Hierarchy and Susceptibility to Degradation by Ultraviolet Radiation.
2008,
Pubmed
Sakai,
Type VII collagen is a major structural component of anchoring fibrils.
1986,
Pubmed
Senadheera,
Sea Cucumber Derived Type I Collagen: A Comprehensive Review.
2020,
Pubmed
,
Echinobase
Subhan,
Marine Collagen: An Emerging Player in Biomedical applications.
2015,
Pubmed
Theocharis,
Extracellular matrix structure.
2016,
Pubmed
Thurmond,
Morphology and biomechanics of the microfibrillar network of sea cucumber dermis.
1996,
Pubmed
,
Echinobase
Tian,
Collagen fibrils of sea cucumber (Apostichopus japonicus) are heterotypic.
2020,
Pubmed
,
Echinobase
Tipper,
Purification, characterization and cloning of tensilin, the collagen-fibril binding and tissue-stiffening factor from Cucumaria frondosa dermis.
2002,
Pubmed
,
Echinobase
Trotter,
Molecular structure and functional morphology of echinoderm collagen fibrils.
1994,
Pubmed
,
Echinobase
Wang,
Investigation of structural proteins in sea cucumber (Apostichopus japonicus) body wall.
2020,
Pubmed
,
Echinobase
Wilkie,
Mutable collagenous tissue: overview and biotechnological perspective.
2005,
Pubmed
,
Echinobase
Zhong,
Isolation and characterization of collagen from the body wall of sea cucumber Stichopus monotuberculatus.
2015,
Pubmed
,
Echinobase
