ECB-ART-42750
Bioorg Med Chem Lett
2013 Mar 15;236:1823-7. doi: 10.1016/j.bmcl.2013.01.032.
Show Gene links
Show Anatomy links
Pyrrole and furan oligoglycosides from the starfish Asterina batheri and their inhibitory effect on the production of pro-inflammatory cytokines in lipopolysaccharide-stimulated bone marrow-derived dendritic cells.
???displayArticle.abstract???
Three new pyrrole oligoglycosides, astebatheriosides A-C (1-3), and a new furan oligoglycoside, astebatherioside D (4), were isolated from the starfish Asterina batheri by various chromatographic methods. Their structures were elucidated by spectroscopic and chemical methods. Compounds 2, 3, and 4 moderately inhibited IL-12 p40 production in lipopolysaccharide (LPS)-stimulated bone marrow-derived dendritic cells (BMDCs) with IC50 values of 36.4, 31.6, and 22.8μM, respectively.
???displayArticle.pubmedLink??? 23395633
???displayArticle.link??? Bioorg Med Chem Lett
Genes referenced: LOC593824