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Polymers (Basel)
2022 Nov 08;1422:. doi: 10.3390/polym14224806.
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Silk Fibroin Hydrogels Incorporated with the Antioxidant Extract of Stryphnodendron adstringens Bark.
de Brito VP
,
de Souza Ribeiro MM
,
Viganó J
,
de Moraes MA
,
Veggi PC
.
Abstract
Barbatimão (Stryphnodendron adstringens) is a Brazilian medicinal plant known for its pharmacological properties, including healing activity related to its phenolic composition, which is chiefly given by tannins. In order to preserve its stability and bioactivity, barbatimão extracts can be incorporated into (bio-)polymeric matrixes, of which silk fibroin stands out due to its versatility and tunable properties. This work aimed to obtain barbatimão bark extract rich in phenolic compounds and evaluate its incorporation in fibroin hydrogels. From the extraction process, it was observed that the PG (propylene glycol) extract presented a higher global yield (X0) and phenolic compounds (TPC) than the ET (ethanol) extract. Furthermore, the antioxidant activity (ORAC and FRAP) was similar between both extracts. Regarding the hydrogels, morphological, chemical, thermal, and mechanical characterizations were performed to understand the influence of the barbatimão extract and the solvent on the fibroin hydrogel properties. As a result, the hydrogels containing the barbatimão PG extract (BT/PG hydrogels) showed the better physical-chemical and structural performance. Therefore, these hydrogels should be further investigated regarding their potential in medical and pharmaceutical applications, especially in wound healing.
Alara,
Extraction of phenolic compounds: A review.
2021, Pubmed
Alara,
Extraction of phenolic compounds: A review.
2021,
Pubmed
Baurin,
Preliminary screening of some tropical plants for anti-tyrosinase activity.
2002,
Pubmed
Dutra,
Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives.
2016,
Pubmed
Guziewicz,
Lyophilized silk fibroin hydrogels for the sustained local delivery of therapeutic monoclonal antibodies.
2011,
Pubmed
Hadi,
Alginate/aloe vera films reinforced with tragacanth gum.
2022,
Pubmed
Haslam,
Natural polyphenols (vegetable tannins) as drugs: possible modes of action.
1996,
Pubmed
Holetz,
Biological effects of extracts obtained from Stryphnodendron adstringens on Herpetomonas samuelpessoai.
2005,
Pubmed
Hossain,
Optimization of ultrasound assisted extraction of antioxidant compounds from marjoram (Origanum majorana L.) using response surface methodology.
2012,
Pubmed
Inpanya,
Effects of the blended fibroin/aloe gel film on wound healing in streptozotocin-induced diabetic rats.
2012,
Pubmed
Ishida,
Activity of tannins from Stryphnodendron adstringens on Cryptococcus neoformans: effects on growth, capsule size and pigmentation.
2009,
Pubmed
Jauregi,
Whey proteins-polyphenols interactions can be exploited to reduce astringency or increase solubility and stability of bioactives in foods.
2021,
Pubmed
Jauregi,
Astringency reduction in red wine by whey proteins.
2016,
Pubmed
Jing,
Fabrication of Hybrid Hydrogels from Silk Fibroin and Tannic Acid with Enhanced Gelation and Antibacterial Activities.
2019,
Pubmed
Kim,
Nature-Derived Aloe Vera Gel Blended Silk Fibroin Film Scaffolds for Cornea Endothelial Cell Regeneration and Transplantation.
2016,
Pubmed
Kim,
Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin.
2005,
Pubmed
Lee,
Hydrogels for delivery of bioactive agents: a historical perspective.
2013,
Pubmed
Li,
Curcumin-functionalized silk materials for enhancing adipogenic differentiation of bone marrow-derived human mesenchymal stem cells.
2015,
Pubmed
Lissner,
Constraints of propylene glycol degradation at low temperatures and saturated flow conditions.
2015,
Pubmed
Matsumoto,
Mechanisms of silk fibroin sol-gel transitions.
2006,
Pubmed
Ou,
Determination of total antioxidant capacity by oxygen radical absorbance capacity (ORAC) using fluorescein as the fluorescence probe: First Action 2012.23.
2013,
Pubmed
Pham,
A dual synergistic of curcumin and gelatin on thermal-responsive hydrogel based on Chitosan-P123 in wound healing application.
2019,
Pubmed
Qi,
A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures.
2017,
Pubmed
Rashmi,
Phenolic acids from vegetables: A review on processing stability and health benefits.
2020,
Pubmed
Ribeiro,
Antileishmanial activity of standardized fractions of Stryphnodendron obovatum (Barbatimão) extract and constituent compounds.
2015,
Pubmed
Ribeiro,
The role of dialysis and freezing on structural conformation, thermal properties and morphology of silk fibroin hydrogels.
2014,
Pubmed
Sousa,
Optimization of Ultrasound-assisted extraction of polyphenols, tannins and epigallocatechin gallate from barks of Stryphnodendron adstringens (Mart.) Coville bark extracts.
2014,
Pubmed
Souza,
Plants from Brazilian Cerrado with potent tyrosinase inhibitory activity.
2012,
Pubmed
Souza-Moreira,
Stryphnodendron Species Known as "Barbatimão": A Comprehensive Report.
2018,
Pubmed
Tamada,
New process to form a silk fibroin porous 3-D structure.
2005,
Pubmed
Vepari,
Silk as a Biomaterial.
2007,
Pubmed
Viganó,
Extraction of bioactive compounds from defatted passion fruit bagasse (Passiflora edulis sp.) applying pressurized liquids assisted by ultrasound.
2020,
Pubmed
,
Echinobase
Wenk,
Silk fibroin as a vehicle for drug delivery applications.
2011,
Pubmed
