Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
J Mol Evol
1991 Jun 01;326:511-20. doi: 10.1007/bf02102653.
Show Gene links
Show Anatomy links
Strand-specific nucleotide composition bias in echinoderm and vertebrate mitochondrial genomes.
Asakawa S
,
Kumazawa Y
,
Araki T
,
Himeno H
,
Miura K
,
Watanabe K
.
???displayArticle.abstract???
The gene organization of starfish mitochondrial DNA is identical with that of the sea urchin counterpart except for a reported inversion of an approximately 4.6-kb segment containing two structural genes for NADH dehydrogenase subunits 1 and 2 (ND 1 and ND 2). When the codon usage of each structural gene in starfish, sea urchin, and vertebrate mitochondrial DNAs is examined, it is striking that codons ending in T and G are preferentially used more for heavy strand-encoded genes, including starfish ND 1 and ND 2, than for light strand-encoded genes, including sea urchin ND 1 and ND 2. On the contrary, codons ending in A and C are preferentially used for the light strand-encoded genes rather than for the heavy strand-encoded ones. Moreover, G-U base pairs are more frequently found in the possible secondary structures of heavy strand-encoded tRNAs than in those of light strand-encoded tRNAs. These observations suggest the existence of a certain constraint operating on mitochondrial genomes from various animal phyla, which results in the accumulation of G and T on one strand, and A and C on the other.
Aloni,
Expression of the mitochondrial genome in HeLa cells. II. Evidence for complete transcription of mitochondrial DNA.
1971, Pubmed
Aloni,
Expression of the mitochondrial genome in HeLa cells. II. Evidence for complete transcription of mitochondrial DNA.
1971,
Pubmed
Anderson,
Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome.
1982,
Pubmed
Anderson,
Sequence and organization of the human mitochondrial genome.
1981,
Pubmed
Bibb,
Sequence and gene organization of mouse mitochondrial DNA.
1981,
Pubmed
Bogenhagen,
Mechanism of mitochondrial DNA replication in mouse L-cells: kinetics of synthesis and turnover of the initiation sequence.
1978,
Pubmed
Bolden,
DNA polymerase of mitochondria is a gamma-polymerase.
1977,
Pubmed
Brown,
Mechanisms of evolution in animal mitochondrial DNA.
1981,
Pubmed
Brown,
Mitochondrial DNA sequences of primates: tempo and mode of evolution.
1982,
Pubmed
Cantatore,
The complete nucleotide sequence, gene organization, and genetic code of the mitochondrial genome of Paracentrotus lividus.
1989,
Pubmed
,
Echinobase
Chang,
Priming of human mitochondrial DNA replication occurs at the light-strand promoter.
1985,
Pubmed
Clary,
The mitochondrial DNA molecular of Drosophila yakuba: nucleotide sequence, gene organization, and genetic code.
1985,
Pubmed
Clayton,
The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria.
1974,
Pubmed
Desjardins,
Sequence and gene organization of the chicken mitochondrial genome. A novel gene order in higher vertebrates.
1990,
Pubmed
Doda,
Elongation of displacement-loop strands in human and mouse mitochondrial DNA is arrested near specific template sequences.
1981,
Pubmed
Gadaleta,
The complete nucleotide sequence of the Rattus norvegicus mitochondrial genome: cryptic signals revealed by comparative analysis between vertebrates.
1989,
Pubmed
Goddard,
Origin and direction of replication in mitochondrial DNA molecules from the genus Drosophila.
1980,
Pubmed
Hasegawa,
Heterogeneity of tempo and mode of mitochondrial DNA evolution among mammalian orders.
1989,
Pubmed
Heckman,
Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs.
1980,
Pubmed
Himeno,
Unusual genetic codes and a novel gene structure for tRNA(AGYSer) in starfish mitochondrial DNA.
1987,
Pubmed
,
Echinobase
Ikemura,
Correlation between the abundance of yeast transfer RNAs and the occurrence of the respective codons in protein genes. Differences in synonymous codon choice patterns of yeast and Escherichia coli with reference to the abundance of isoaccepting transfer RNAs.
1982,
Pubmed
Ikemura,
Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system.
1981,
Pubmed
Jacobs,
Sea urchin egg mitochondrial DNA contains a short displacement loop (D-loop) in the replication origin region.
1989,
Pubmed
,
Echinobase
Jacobs,
Nucleotide sequence and gene organization of sea urchin mitochondrial DNA.
1988,
Pubmed
,
Echinobase
Jacobs,
Conserved tRNA gene cluster in starfish mitochondrial DNA.
1989,
Pubmed
,
Echinobase
Jukes,
Evolution of anticodons: variations in the genetic code.
1987,
Pubmed
Jukes,
Silent nucleotide substitutions and G + C content of some mitochondrial and bacterial genes.
1986,
Pubmed
Kumazawa,
The aminoacylation of structurally variant phenylalanine tRNAs from mitochondria and various nonmitochondrial sources by bovine mitochondrial phenylalanyl-tRNA synthetase.
1989,
Pubmed
Kunkel,
The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis.
1985,
Pubmed
Martens,
Mechanism of mitochondrial DNA replication in mouse L-cells: localization and sequence of the light-strand origin of replication.
1979,
Pubmed
Muto,
The guanine and cytosine content of genomic DNA and bacterial evolution.
1987,
Pubmed
Ohama,
Role of GC-biased mutation pressure on synonymous codon choice in Micrococcus luteus, a bacterium with a high genomic GC-content.
1990,
Pubmed
Osawa,
Directional mutation pressure and transfer RNA in choice of the third nucleotide of synonymous two-codon sets.
1988,
Pubmed
Osawa,
Codon reassignment (codon capture) in evolution.
1989,
Pubmed
Robberson,
Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells.
1972,
Pubmed
Roe,
The complete nucleotide sequence of the Xenopus laevis mitochondrial genome.
1985,
Pubmed
Smith,
Gene arrangement in sea star mitochondrial DNA demonstrates a major inversion event during echinoderm evolution.
1989,
Pubmed
,
Echinobase
Sprinzl,
Compilation of tRNA sequences and sequences of tRNA genes.
1989,
Pubmed
SUEOKA,
On the genetic basis of variation and heterogeneity of DNA base composition.
1962,
Pubmed
Takeishi,
Computer analysis of the sequence relationships among 4.5S RNA molecular species from various sources.
1982,
Pubmed
Thomas,
Shifting constraints on tRNA genes during mitochondrial DNA evolution in animals.
1989,
Pubmed
,
Echinobase
Wolstenholme,
Bizarre tRNAs inferred from DNA sequences of mitochondrial genomes of nematode worms.
1987,
Pubmed
Yokogawa,
Purification and characterization of two serine isoacceptor tRNAs from bovine mitochondria by using a hybridization assay method.
1989,
Pubmed
