Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
???displayArticle.abstract??? DNA polymerase alpha and beta were identified in the urchin, Strongylocentrotus purpuratus. The DNA polymerase beta sedimented at 3.4 S, constituted 5% of total DNA polymerase activity, and was resistant to N-ethylmaleimide and high ionic strength. The polymerase alpha sedimented at 6--8 S, was inhibited by N-ethylmalemide or 0.1 M (NH4)2SO4, and was dependent upon glycerol for preservation of activity. Both the polymerases alpha and beta were nuclear associated in embryos. The DNA polymerase alpha was markedly heterogeneous on DEAE-Sephadex ion exchange and showed three modal polymerase species. These polymerase alpha species were indistinguishable by template activity assays but the DNA polymerase associated ribonucleotidyl transferase (Biochemistry 75 : 3106-3113, 1976) was found predominantly with only one of the DNA polymerase alpha species.
APOSHIAN,
Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme.
1962, Pubmed
APOSHIAN,
Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme.
1962,
Pubmed
Bolden,
DNA polymerase of mitochondria is a gamma-polymerase.
1977,
Pubmed
Brakel,
Replication of poly dA and poly rA by a drosophila DNA polymerase.
1978,
Pubmed
Bull,
Inactivation of E. coli RNA polymerase by pyridoxal 5'-phosphate: identificationof a low pKa lysine as the modified residue.
1975,
Pubmed
Chang,
Low molecular weight deoxyribonucleic acid polymerase from rabbit bone marrow.
1972,
Pubmed
Chang,
Phylogeny of DNA polymerase-beta.
1976,
Pubmed
De Petrocellis,
Separation and partial characterization of DNA polymerases in sea urchin Paracentrotus lividus eggs.
1976,
Pubmed
,
Echinobase
Fansler,
Sea urchin nuclear DNA polymerase. II. Changing localization during early development.
1969,
Pubmed
,
Echinobase
Fisher,
DNA polymerase-alpha. Purification and structural characterization of the near homogeneous enzyme from human KB cells.
1977,
Pubmed
HINEGARDNER,
THE DNA SYNTHETIC PERIOD DURING EARLY DEVELOPMENT OF THE SEA URCHIN EGG.
1964,
Pubmed
,
Echinobase
Hachmann,
High-molecular-weight DNA polymerases from mouse myeloma. Purification and properties of three enzymes.
1975,
Pubmed
Holmer,
The occurrence of multiple activities in the high-molecular-weight DNA polymerase fraction of mammalian tissues. A preliminary study of some of their properties.
1974,
Pubmed
Holmes,
DNA polymerases of eukaryotes.
1975,
Pubmed
Kirkegaard,
Gradient sievorptive chromatography. A focusing system for the separation of cellular components.
1973,
Pubmed
Loeb,
Sea urchin nuclear DNA polymerase. I. Localization in nuclei during rapid DNA synthesis.
1969,
Pubmed
,
Echinobase
Loeb,
Purification and properties of deoxyribonucleic acid polymerase from nuclei of sea urchin embryos.
1969,
Pubmed
,
Echinobase
Martial,
Inactivation of rat liver RNA polymerases I and II and yeast RNA polymerase I by pyrodixal 5'-phosphate. Evidence for the participation of lysyl residues at the active site.
1975,
Pubmed
Matsukage,
Multiple forms of DNA polymerase in mouse myeloma.
1974,
Pubmed
Mazia,
Chromosome cycles turned on in unfertilized sea urchin eggs exposed to NH4OH.
1974,
Pubmed
,
Echinobase
Morris,
Nucleic acid polymerizing enzymes in developing Strongylocentrotus franciscanus embryos.
1976,
Pubmed
,
Echinobase
Roeder,
Multiple ribonucleic acid polymerases and ribonucleic acid synthesis during sea urchin development.
1970,
Pubmed
,
Echinobase
Vallee,
ZINC, A COMPONENT OF YEAST ALCOHOL DEHYDROGENASE.
1955,
Pubmed
Venton,
Inhibition of nucleotidyl transferase enzymes by metal ions in combination with 5-amino-1-formylisoquinoline thiosemicarbazone.
1977,
Pubmed
,
Echinobase
Weissbach,
Vertebrate DNA polymerases.
1975,
Pubmed
YONEDA,
DEOXYNUCLEOTIDE-POLYMERIZING ENZYMES OF CALF THYMUS GLAND. I. LARGE SCALE PURIFICATION OF TERMINAL AND REPLICATIVE DEOXYNUCLEOTIDYL TRANSFERASES.
1965,
Pubmed
Young,
Synthesis of protein for DNA replication and cleavage events in the sand dollar embryo.
1969,
Pubmed
,
Echinobase
