Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
J Tradit Complement Med
2018 Jul 01;83:341-351. doi: 10.1016/j.jtcme.2017.06.007.
Show Gene links
Show Anatomy links
Medicinal and health benefit effects of functional sea cucumbers.
Pangestuti R
,
Arifin Z
.
Abstract
Sea cucumbers have long been used as food and traditional medicine in Asian countries with Stichopus hermanni, Thelenota ananas, Thelenota anax, Holothuria fuccogilva, and Actinopyga mauritiana as most highly-valued species. These organisms are potential source of high value-added compounds with therapeutic properties such as triterpene glycosides, carotenoids, bioactive peptides, vitamins, minerals, fatty acids, collagens, gelatins, chondroitin sulfates, amino acids. In the recent years, health benefit effects of sea cucumbers have been validated through scientific research and have shown medicinal value such as wound healing, neuroprotective, antitumor, anticoagulant, antimicrobial, and antioxidant. These functional materials lead to potential development in various foods and biomedicine industries. In this review, we have presented a general view of major medicinal and health benefit effects of functional sea cucumbers from Asia region. The structural significance and the potential application of sea cucumber-derived functional materials as well as their nutritional value are also discussed.
Aminin,
Anticancer activity of sea cucumber triterpene glycosides.
2015,
Pubmed
,
Echinobase
Assawasuparerk,
Scabraside D Extracted from Holothuria scabra Induces Apoptosis and Inhibits Growth of Human Cholangiocarcinoma Xenografts in Mice.
2016,
Pubmed
,
Echinobase
Baharara,
The Cytotoxicity of Dacarbazine Potentiated by Sea Cucumber Saponin in Resistant B16F10 Melanoma Cells through Apoptosis Induction.
2016,
Pubmed
,
Echinobase
Bahrami,
Discovery of novel saponins from the viscera of the sea cucumber Holothuria lessoni.
2014,
Pubmed
,
Echinobase
Choi,
Determination of toxic heavy metals in Echinodermata and Chordata species from South Korea.
2014,
Pubmed
,
Echinobase
Copat,
Heavy metals concentrations in fish and shellfish from eastern Mediterranean Sea: consumption advisories.
2013,
Pubmed
Dakrory,
Protective and curative effects of the sea cucumber Holothuria atra extract against DMBA-induced hepatorenal diseases in rats.
2015,
Pubmed
,
Echinobase
Dang,
Two new triterpene glycosides from the Vietnamese sea cucumber Holothuria scabra.
2007,
Pubmed
,
Echinobase
Dhinakaran,
Bioactive compounds from Holothuria atra of Indian ocean.
2014,
Pubmed
,
Echinobase
Esmat,
Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats.
2013,
Pubmed
,
Echinobase
Freitas,
Marine biotechnology advances towards applications in new functional foods.
2012,
Pubmed
Gao,
β-Eliminative depolymerization of the fucosylated chondroitin sulfate and anticoagulant activities of resulting fragments.
2015,
Pubmed
,
Echinobase
Gowda,
T-antigen binding lectin with antibacterial activity from marine invertebrate, sea cucumber (Holothuria scabra): possible involvement in differential recognition of bacteria.
2008,
Pubmed
,
Echinobase
Grunert,
European consumers' acceptance of functional foods.
2010,
Pubmed
Guo,
Saponin-enriched sea cucumber extracts exhibit an antiobesity effect through inhibition of pancreatic lipase activity and upregulation of LXR-β signaling.
2016,
Pubmed
,
Echinobase
Han,
A novel sulfated holostane glycoside from sea cucumber Holothuria leucospilota.
2010,
Pubmed
,
Echinobase
Han,
Two new cytotoxic triterpene glycosides from the sea cucumber Holothuria scabra.
2009,
Pubmed
,
Echinobase
Huang,
The depolymerized fucosylated chondroitin sulfate from sea cucumber potently inhibits HIV replication via interfering with virus entry.
2013,
Pubmed
,
Echinobase
Kim,
Triterpene glycosides from sea cucumbers and their biological activities.
2012,
Pubmed
,
Echinobase
Krupodorova,
Some macronutrient content in mycelia and culture broth of medicinal mushrooms cultivated on amaranth flour.
2012,
Pubmed
Lawrence,
Bioactivity as an options value of sea cucumbers in the Egyptian Red Sea.
2010,
Pubmed
,
Echinobase
Luo,
Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers.
2013,
Pubmed
,
Echinobase
Masre,
Quantitative analysis of sulphated glycosaminoglycans content of Malaysian sea cucumber Stichopus hermanni and Stichopus vastus.
2012,
Pubmed
,
Echinobase
Pangestuti,
Optimization of hydrolysis conditions, isolation, and identification of neuroprotective peptides derived from seahorse Hippocampus trimaculatus.
2013,
Pubmed
Park,
Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers.
2014,
Pubmed
,
Echinobase
Rajamohan,
Lysine: arginine ratio of a protein influences cholesterol metabolism. Part 1--Studies on sesame protein having low lysine: arginine ratio.
1997,
Pubmed
Ridzwan,
Screening for antibacterial agents in three species of sea cucumbers from coastal areas of Sabah.
1995,
Pubmed
,
Echinobase
Soltani,
Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber.
2014,
Pubmed
,
Echinobase
Soltani,
Putative mechanism for apoptosis-inducing properties of crude saponin isolated from sea cucumber (Holothuria leucospilota) as an antioxidant compound.
2015,
Pubmed
,
Echinobase
Tsushima,
Comparative biochemical studies of carotenoids in catfishes.
2002,
Pubmed
Wen,
Elemental composition of commercial sea cucumbers (holothurians).
2010,
Pubmed
,
Echinobase
Wen,
Chemical composition and nutritional quality of sea cucumbers.
2010,
Pubmed
,
Echinobase
Wu,
Preparation and characterization of molecular weight fractions of glycosaminoglycan from sea cucumber Thelenata ananas using free radical depolymerization.
2010,
Pubmed
,
Echinobase
Yu,
Structure elucidation of fucoidan composed of a novel tetrafucose repeating unit from sea cucumber Thelenota ananas.
2014,
Pubmed
,
Echinobase
Yun,
Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
2012,
Pubmed
,
Echinobase
Zhong,
Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Cucumaria frondosa).
2007,
Pubmed
,
Echinobase
Zohdi,
Sea cucumber (Stichopus hermanii) based hydrogel to treat burn wounds in rats.
2011,
Pubmed
,
Echinobase
