ECB-ART-47001
Nat Prod Commun
2016 Sep 01;119:1247-1250.
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Aphelasteroside F, a new Asterosaponin from the Far Eastern Starfish Aphelasterias japonica.
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A new asterosaponin aphelasteroside F (1) was isolated from the ethanolic extract of the Far Eastern starfish Aphelasterias japonica along with the previously known ophidianoside F (2). The structure of 1 was elucidated by extensive use of NMR and ESI-MS techniques, and chemical transformations. Compound 1 contains a new type of asterosaponin carbohydrate chain linked to C-6 of the steroid aglycone aphelaketotriol. Compounds 1 and 2 at non-toxic concentrations slightly inhibited cell proliferation and colony formation of the cancer melanoma cell lines SK-Mel-28, SK-Mel-5, and RPMI-7951.
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Genes referenced: LOC100893907 LOC115919910