ECB-ART-40127
Chem Pharm Bull (Tokyo)
2007 Mar 01;553:459-61. doi: 10.1248/cpb.55.459.
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A new 2,3-dimethyl butenolide from the brittle star Ophiomastix mixta.
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A new butenolide (1) was isolated, along with a known acyclic polyhalogenated monoterpene (2), from the brittle star Ophiomastix mixta. The structures were defined by analysis and comparision of the spectral data with those in the literature. The 2,3-dimethyl butenolide (1) is uncommon and first encountered in a marine organism. The compounds were tested for cytotoxicity against a panel of five human solid tumor cell lines and displayed mild to significant activity.
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Genes referenced: LOC100893907 LOC115919910