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Proc Natl Acad Sci U S A
1974 Jul 01;717:2900-4. doi: 10.1073/pnas.71.7.2900.
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Isolation and some properties of the genes coding for histone proteins.
Birnstiel M
,
Telford J
,
Weinberg E
,
Stafford D
.
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The DNA coding for histone proteins, together with the intervening spacer DNA, has been isolated from the sea urchin, Psammechinus miliaris, by repeated centrifugation on CsCl-asctinomycin gradients. The biophysical data show that a major portion of the spacer is 37% G+C and very divergent in sequence, while the DNA segments coding for histone proteins are high in G+C and have diverged to a lesser extent within the species.
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