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World J Microbiol Biotechnol
2013 Mar 01;293:515-22. doi: 10.1007/s11274-012-1205-0.
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Profile and multidrug resistance determinants of Chryseobacterium indologenes from seawater and marine fauna.
Maravić A
,
Skočibušić M
,
Samanić I
,
Puizina J
.
Abstract
The aim of this study was to investigate the prevalence and genetic basis of multidrug resistance in Chryseobacterium indologenes from seawater and marine invertebrates used for human consumption, in Kaštela Bay, Adriatic Sea, Croatia. Out of 16 samples of seawater, Mediterranean mussel (Mytilus galloprovincialis Lam.), Rayed Mediterranean limpets (Patella caerulea L.) and Purple sea urchins (Paracentrotus lividus Lam.) collected, 15 were positive for C. indologenes. In total, 41 isolates were randomly selected and tested for antibiotic susceptibility by disc-diffusion and broth microdilution methods. PCR was used to detect alleles encoding extended-spectrum (ESBLs) and metallo-β-lactamases (MBLs). The clonality of β-lactamase-producing strains was evaluated by random amplified polymorphic DNA (RAPD) analysis. All C. indologenes isolates showed multiple resistance to at least 9 out of 16 antibiotics tested. Lowest resistance rates were found for piperacillin (9.7 %) and ciprofloxacin (24.4 %), whereas only piperacillin/tazobactam and trimethoprim/sulfamethoxazole showed 100 % activity. More than half of isolates carried bla (IND)-type gene, including 2 isolates carrying bla (IND-2) and 21 carrying bla (IND-7), that was identified as a major MBL genotype in isolates from Adriatic Sea. RAPD typing of IND-producing isolates revealed 6 major groups with no predominant clone in population. The presence of multidrug resistant and IND-producing C. indologenes in marine environment, including marine fauna, pose a risk for transmitting this opportunistic pathogen to humans through recreation or consummation of seafood. In addition, the antibiotic susceptibility test results have practical relevance for empirical treatment of C. indologenes infections.
Bayraktar,
Postoperative Chryseobacterium indologenes bloodstream infection caused by contamination of distillate water.
2007, Pubmed
Bayraktar,
Postoperative Chryseobacterium indologenes bloodstream infection caused by contamination of distillate water.
2007,
Pubmed
Bellais,
Genetic diversity of carbapenem-hydrolyzing metallo-beta-lactamases from Chryseobacterium (Flavobacterium) indologenes.
2000,
Pubmed
Bellais,
Molecular characterization of a carbapenem-hydrolyzing beta-lactamase from Chryseobacterium (Flavobacterium) indologenes.
1999,
Pubmed
Bernardet,
Polyphasic study of Chryseobacterium strains isolated from diseased aquatic animals.
2005,
Pubmed
Bogomolni,
Victims or vectors: a survey of marine vertebrate zoonoses from coastal waters of the Northwest Atlantic.
2008,
Pubmed
Chen,
Clinical and epidemiological features of Chryseobacterium indologenes infections: analysis of 215 cases.
2013,
Pubmed
Chou,
Clinical characteristics, antimicrobial susceptibilities, and outcomes of patients with Chryseobacterium indologenes bacteremia in an intensive care unit.
2011,
Pubmed
DePaola,
Bacterial and viral pathogens in live oysters: 2007 United States market survey.
2010,
Pubmed
Ellington,
Multiplex PCR for rapid detection of genes encoding acquired metallo-beta-lactamases.
2007,
Pubmed
Hsueh,
Increasing incidence of nosocomial Chryseobacterium indologenes infections in Taiwan.
1997,
Pubmed
Kirby,
Antimicrobial susceptibility and epidemiology of a worldwide collection of Chryseobacterium spp: report from the SENTRY Antimicrobial Surveillance Program (1997-2001).
2004,
Pubmed
Lin,
Heterogeneity of bla(IND) metallo-beta-lactamase-producing Chryseobacterium indologenes isolates detected in Hefei, China.
2008,
Pubmed
Lin,
Clinical and microbiological characteristics of Chryseobacterium indologenes bacteremia.
2010,
Pubmed
Maravić,
Antibiotic susceptibility profiles and first report of TEM extended-spectrum β-lactamase in Pseudomonas fluorescens from coastal waters of the Kaštela Bay, Croatia.
2012,
Pubmed
Matyar,
Antibacterial agents and heavy metal resistance in Gram-negative bacteria isolated from seawater, shrimp and sediment in Iskenderun Bay, Turkey.
2008,
Pubmed
Perilli,
Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes.
2007,
Pubmed
Pitout,
Detection of Pseudomonas aeruginosa producing metallo-beta-lactamases in a large centralized laboratory.
2005,
Pubmed
Reynaud,
[A severe form of Chryseobacterium indologenes pneumonia in an immunocompetent patient].
2007,
Pubmed
Rose,
Occurrence and patterns of antibiotic resistance in vertebrates off the Northeastern United States coast.
2009,
Pubmed
Sader,
Antimicrobial susceptibility of uncommonly isolated non-enteric Gram-negative bacilli.
2005,
Pubmed
Uyaguari,
Acute effects of the antibiotic oxytetracycline on the bacterial community of the grass shrimp, Palaemonetes pugio.
2009,
Pubmed
Yabuuchi,
Genotypic and phenotypic differentiation of Flavobacterium indologenes Yabuuchi et al 1983 from Flavobacterium gleum Holmes et al 1984.
1990,
Pubmed
Zamora,
Chryseobacterium oncorhynchi sp. nov., isolated from rainbow trout (Oncorhynchus mykiss).
2012,
Pubmed
Zeba,
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
2009,
Pubmed
du Moulin,
Airway colonization by Flavobacterium in an intensive care unit.
1979,
Pubmed
