ECB-ART-50496
Curr Top Dev Biol
2022 Jan 01;146:25-48. doi: 10.1016/bs.ctdb.2021.10.002.
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Development of a larval nervous system in the sea urchin.
Abstract
This review reports recent findings on the specification and patterning of neurons that establish the larval nervous system of the sea urchin embryo. Neurons originate in three regions of the embryo. Perturbation analyses enabled construction of gene regulatory networks controlling the several neural cell types. Many of the mechanisms described reflect shared features of all metazoans and others are conserved among deuterostomes. This nervous system with a very small number of neurons supports the feeding and swimming behaviors of the larva until metamorphosis when an adult nervous system replaces that system.
PubMed ID: 35152985
PMC ID: PMC9968406
Article link: Curr Top Dev Biol
Grant support: [+]
R01 HD014483 NICHD NIH HHS
References [+] :
Angerer,
The evolution of nervous system patterning: insights from sea urchin development.
2011, Pubmed,
Echinobase
Angerer, The evolution of nervous system patterning: insights from sea urchin development. 2011, Pubmed , Echinobase
Angerer, A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis. 2000, Pubmed , Echinobase
Artavanis-Tsakonas, Notch and the molecular genetics of neuroblast segregation in Drosophila. 1990, Pubmed
Artavanis-Tsakonas, Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster. 1983, Pubmed
Ashe, Local inhibition and long-range enhancement of Dpp signal transduction by Sog. 1999, Pubmed
Barsi, cis-Regulatory control of the initial neurogenic pattern of onecut gene expression in the sea urchin embryo. 2016, Pubmed , Echinobase
Barsi, Geometric control of ciliated band regulatory states in the sea urchin embryo. 2015, Pubmed , Echinobase
Bolouri, The gene regulatory network basis of the "community effect," and analysis of a sea urchin embryo example. 2010, Pubmed , Echinobase
Bradham, p38 MAPK is essential for secondary axis specification and patterning in sea urchin embryos. 2006, Pubmed , Echinobase
Bradham, Chordin is required for neural but not axial development in sea urchin embryos. 2009, Pubmed , Echinobase
Burke, A genomic view of the sea urchin nervous system. 2006, Pubmed , Echinobase
Burke, Neuron-specific expression of a synaptotagmin gene in the sea urchin Strongylocentrotus purpuratus. 2006, Pubmed , Echinobase
Chang, Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation. 2007, Pubmed
Cheatle Jarvela, A gene regulatory network for apical organ neurogenesis and its spatial control in sea star embryos. 2016, Pubmed , Echinobase
Coffman, Oral-aboral axis specification in the sea urchin embryo III. Role of mitochondrial redox signaling via H2O2. 2009, Pubmed , Echinobase
Coffman, Oral-aboral axis specification in the sea urchin embryo. I. Axis entrainment by respiratory asymmetry. 2001, Pubmed , Echinobase
Coffman, Mitochondria, redox signaling and axis specification in metazoan embryos. 2007, Pubmed , Echinobase
Coffman, Oral-aboral axis specification in the sea urchin embryo II. Mitochondrial distribution and redox state contribute to establishing polarity in Strongylocentrotus purpuratus. 2004, Pubmed , Echinobase
Coffman, Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity. 2014, Pubmed , Echinobase
Duboc, Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo. 2010, Pubmed , Echinobase
Duboc, Lefty acts as an essential modulator of Nodal activity during sea urchin oral-aboral axis formation. 2008, Pubmed , Echinobase
Duboc, Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo. 2004, Pubmed , Echinobase
Duboc, Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side. 2005, Pubmed , Echinobase
Elphick, Molecular characterisation of SALMFamide neuropeptides in sea urchins. 2005, Pubmed , Echinobase
Floc'hlay, Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo. 2021, Pubmed , Echinobase
Garner, Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms. 2016, Pubmed , Echinobase
Gurdon, A community effect in animal development. NULL, Pubmed
Haillot, The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo. 2015, Pubmed , Echinobase
Hemmati-Brivanlou, Inhibition of activin receptor signaling promotes neuralization in Xenopus. 1994, Pubmed
Hemmati-Brivanlou, Vertebrate embryonic cells will become nerve cells unless told otherwise. 1997, Pubmed
Hinman, Embryonic neurogenesis in echinoderms. 2018, Pubmed , Echinobase
Khadka, A novel gene's role in an ancient mechanism: secreted Frizzled-related protein 1 is a critical component in the anterior-posterior Wnt signaling network that governs the establishment of the anterior neuroectoderm in sea urchin embryos. 2018, Pubmed , Echinobase
Lapraz, A deuterostome origin of the Spemann organiser suggested by Nodal and ADMPs functions in Echinoderms. 2015, Pubmed , Echinobase
Lapraz, Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network. 2009, Pubmed , Echinobase
Lim, Arx Expression Suppresses Ventralization of the Developing Dorsal Forebrain. 2019, Pubmed
Logan, Nuclear beta-catenin is required to specify vegetal cell fates in the sea urchin embryo. 1999, Pubmed , Echinobase
Longabaugh, Visualization, documentation, analysis, and communication of large-scale gene regulatory networks. 2009, Pubmed
Lowe, The crowns have eyes: multiple opsins found in the eyes of the crown-of-thorns starfish Acanthaster planci. 2018, Pubmed , Echinobase
Massri, Developmental single-cell transcriptomics in the Lytechinus variegatus sea urchin embryo. 2021, Pubmed , Echinobase
McClay, Neurogenesis in the sea urchin embryo is initiated uniquely in three domains. 2018, Pubmed , Echinobase
Mellott, Notch signaling patterns neurogenic ectoderm and regulates the asymmetric division of neural progenitors in sea urchin embryos. 2017, Pubmed , Echinobase
Modell, Mitochondrial gradients and p38 activity in early sea urchin embryos. 2011, Pubmed , Echinobase
Molina, p38 MAPK as an essential regulator of dorsal-ventral axis specification and skeletogenesis during sea urchin development: a re-evaluation. 2017, Pubmed , Echinobase
Molina, Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo. 2020, Pubmed , Echinobase
Otim, SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis. 2004, Pubmed , Echinobase
Range, Cis-regulatory analysis of nodal and maternal control of dorsal-ventral axis formation by Univin, a TGF-beta related to Vg1. 2007, Pubmed , Echinobase
Range, Canonical and non-canonical Wnt signaling pathways define the expression domains of Frizzled 5/8 and Frizzled 1/2/7 along the early anterior-posterior axis in sea urchin embryos. 2018, Pubmed , Echinobase
Range, Integration of canonical and noncanonical Wnt signaling pathways patterns the neuroectoderm along the anterior-posterior axis of sea urchin embryos. 2013, Pubmed , Echinobase
Range, An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo. 2016, Pubmed , Echinobase
Range, Specification and positioning of the anterior neuroectoderm in deuterostome embryos. 2014, Pubmed , Echinobase
Saudemont, Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. 2010, Pubmed , Echinobase
Sherwood, LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo. 1999, Pubmed , Echinobase
Shimmi, Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo. 2005, Pubmed
Slota, Developmental origin of peripheral ciliary band neurons in the sea urchin embryo. 2020, Pubmed , Echinobase
Slota, Spatial and temporal patterns of gene expression during neurogenesis in the sea urchin Lytechinus variegatus. 2019, Pubmed , Echinobase
Slota, Identification of neural transcription factors required for the differentiation of three neuronal subtypes in the sea urchin embryo. 2018, Pubmed , Echinobase
Smith, Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. 2008, Pubmed
Strathmann, Time and extent of ciliary response to particles in a non-filtering feeding mechanism. 2007, Pubmed , Echinobase
Valencia, Ciliary photoreceptors in sea urchin larvae indicate pan-deuterostome cell type conservation. 2021, Pubmed , Echinobase
Vallier, Enhancing and diminishing gene function in human embryonic stem cells. 2004, Pubmed
Vallier, Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. 2009, Pubmed
van Heijster, A computational model for BMP movement in sea urchin embryos. 2014, Pubmed , Echinobase
Wei, Direct development of neurons within foregut endoderm of sea urchin embryos. 2011, Pubmed , Echinobase
Wei, The sea urchin animal pole domain is a Six3-dependent neurogenic patterning center. 2009, Pubmed , Echinobase
Wei, Neurogenic gene regulatory pathways in the sea urchin embryo. 2016, Pubmed , Echinobase
Wessel, Myosin heavy chain accumulates in dissimilar cell types of the macromere lineage in the sea urchin embryo. 1990, Pubmed , Echinobase
Wood, Neuropeptidergic Systems in Pluteus Larvae of the Sea Urchin Strongylocentrotus purpuratus: Neurochemical Complexity in a "Simple" Nervous System. 2018, Pubmed , Echinobase
Yaguchi, Zinc finger homeobox is required for the differentiation of serotonergic neurons in the sea urchin embryo. 2012, Pubmed , Echinobase
Yaguchi, Evolution of nitric oxide regulation of gut function. 2019, Pubmed , Echinobase
Yaguchi, Sea urchin larvae utilize light for regulating the pyloric opening. 2021, Pubmed , Echinobase
Yaguchi, Expression of tryptophan 5-hydroxylase gene during sea urchin neurogenesis and role of serotonergic nervous system in larval behavior. 2003, Pubmed , Echinobase
Yaguchi, A Wnt-FoxQ2-nodal pathway links primary and secondary axis specification in sea urchin embryos. 2008, Pubmed , Echinobase
Yaguchi, TGFβ signaling positions the ciliary band and patterns neurons in the sea urchin embryo. 2010, Pubmed , Echinobase
Yaguchi, Specification of ectoderm restricts the size of the animal plate and patterns neurogenesis in sea urchin embryos. 2006, Pubmed , Echinobase
Yaguchi, Sp-Smad2/3 mediates patterning of neurogenic ectoderm by nodal in the sea urchin embryo. 2007, Pubmed , Echinobase
Yaguchi, bicaudal-C is required for the formation of anterior neurogenic ectoderm in the sea urchin embryo. 2014, Pubmed , Echinobase
Yaguchi, Fez function is required to maintain the size of the animal plate in the sea urchin embryo. 2011, Pubmed , Echinobase
Yaguchi, Cooperative Wnt-Nodal Signals Regulate the Patterning of Anterior Neuroectoderm. 2016, Pubmed , Echinobase
Yankura, Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning. 2013, Pubmed , Echinobase
Yu, Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity. 2000, Pubmed
Zito, Expression of univin, a TGF-beta growth factor, requires ectoderm-ECM interaction and promotes skeletal growth in the sea urchin embryo. 2003, Pubmed , Echinobase