Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-40527
Chem Biodivers 2007 Dec 01;412:2845-51. doi: 10.1002/cbdv.200790234.
Show Gene links Show Anatomy links

Arguside A: a new cytotoxic triterpene glycoside from the sea cucumber Bohadschia argus Jaeger.

Liu BS , Yi YH , Li L , Zhang SL , Han H , Weng YY , Pan MX .


???displayArticle.abstract???
A new holostane-based triterpene glycoside, arguside A (1), was isolated from the sea cucumber Bohadschia argus, collected in the South China Sea. The structure of the new compound was elucidated by spectroscopic and mass-spectrometric analyses, in combination with chemical transformations. Compound 1 exhibited significant cytotoxicity against different human tumor cell lines, being more active towards HCT-116 cells (IC50 = 0.14 microM) than 10-hydroxycamptothecin (HCP) used as positive control.

???displayArticle.pubmedLink??? 18081095
???displayArticle.link??? Chem Biodivers


Genes referenced: LOC100887844 LOC100893907 LOC115919910