Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-35187
Proc Natl Acad Sci U S A 1980 Jun 01;776:3259-63. doi: 10.1073/pnas.77.6.3259.
Show Gene links Show Anatomy links

Four sizes of transcript produced by a single sea urchin gene expressed in early embryos.

Lee AS , Thomas TL , Lev Z , Britten RJ , Davidson EH .


???displayArticle.abstract???
This report concerns a set of sea urchin egg and embryo transcripts complementary to a single-copy region of a cloned DNA fragment (Sp88). Three distinct 16-cell embryo polysomal RNA species were found to hybridize with this fragment. These RNAs are about 1700, 3000, and 4000 nucleotides (nt) in length, and the same species were identified in unfertilized eggs. A significant fraction of all three species of the egg and early embryo transcripts is polyadenylylated. At gastrula stage Sp88 transcripts are almost completely confined to the nucleus [Lev, Z., Thomas, T. L., Lee, A. S., Angerer, R. C., Britten, R. J. & Davidson, E. H. (1980) Dev. Biol, 75, in press]. The Sp88 transcripts of gastrulae are present as a fourth RNA species approximately 5800 nt in length. The four species share a sequence element of cloned DNA fragment that is about 1000 nt long. These RNAs constitute a set of alternative partially overlapping transcripts from the same genomic region.

???displayArticle.pubmedLink??? 6997875
???displayArticle.pmcLink??? PMC349594
???displayArticle.link??? Proc Natl Acad Sci U S A


Genes referenced: LOC100887844 LOC115919910 LOC583082

References [+] :
Alwine, Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes. 1977, Pubmed