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Mol Cell Biol
1986 Jan 01;61:218-26. doi: 10.1128/mcb.6.1.218-226.1986.
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Sequences from sea urchin TU transposons are conserved among multiple eucaryotic species, including humans.
Liebermann D
,
Hoffman-Liebermann B
,
Troutt AB
,
Kedes L
,
Cohen SN
.
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Sequences homologous to various structural domains of the Strongylocentrotus purpuratus TU family of transposons are present in sea urchin species closely related to S. purpuratus and were found in close proximity to each other in linkage patterns that differed for different species. Sequence homologs of the inverted repeat outer domain (IVR-OD) segment were, in addition, present in a sea urchin related only distantly to S. purpuratus and in all other eucaryotic organisms surveyed. In humans, a polymorphic hybridization pattern was seen for genomic DNA obtained from different individuals. Sequence comparisons revealed that repeated sequence motifs similar to those making up the 15-base-pair direct repeat unit of the IVR-OD domain of the TU elements exist in the IVRs of transposons identified in Drosophila melanogaster and maize and in the transcription control regions of certain eucaryotic viral and cellular genes. The remarkable evolutionary conservation of IVR-OD homologs may reflect a biological role for these sequences in DNA transposition, the regulation of gene expression, or both.
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,
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Baltimore,
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Barker,
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Benoist,
In vivo sequence requirements of the SV40 early promotor region.
1981,
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Benton,
Screening lambdagt recombinant clones by hybridization to single plaques in situ.
1977,
Pubmed
Cairns,
The origin of human cancers.
1981,
Pubmed
Conrad,
Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region.
1982,
Pubmed
Davidson,
Repetitive sequence transcripts in development.
1982,
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,
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Dierks,
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1983,
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Döring,
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Döring,
Barbara McClintock's controlling elements: now at the DNA level.
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Pubmed
Dover,
Molecular drive: a cohesive mode of species evolution.
1982,
Pubmed
Dynan,
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1985,
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Erwin,
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Everett,
The repeated GC-rich motifs upstream from the TATA box are important elements of the SV40 early promoter.
1983,
Pubmed
Finnegan,
Transposable elements in eukaryotes.
1985,
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Fromm,
Deletion mapping of DNA regions required for SV40 early region promoter function in vivo.
1982,
Pubmed
Hartzell,
SV40 deletion mutants lacking the 21-bp repeated sequences are viable, but have noncomplementable deficiencies.
1983,
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Hartzell,
Mapping of the late promoter of simian virus 40.
1984,
Pubmed
Hoffman-Liebermann,
TU elements: a heterogeneous family of modularly structured eucaryotic transposons.
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Pubmed
,
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Johnson,
Insertion of a short repetitive sequence (D88I) in a sea urchin gene: a typical interspersed repeat?
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,
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Kedes,
The organization of sea urchin histone genes.
1975,
Pubmed
,
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Khoury,
Enhancer elements.
1983,
Pubmed
Kleckner,
Transposable elements in prokaryotes.
1981,
Pubmed
Klein,
The role of gene dosage and genetic transpositions in carcinogenesis.
1981,
Pubmed
Levis,
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1982,
Pubmed
Liebermann,
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Pubmed
,
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MCCLINTOCK,
Controlling elements and the gene.
1956,
Pubmed
McCutchan,
DNA sequences similar to those around the simian virus 40 origin of replication are present in the monkey genome.
1981,
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McKnight,
The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence.
1984,
Pubmed
McKnight,
Transcriptional control signals of a eukaryotic protein-coding gene.
1982,
Pubmed
Mishoe,
Simian virus 40 guanine-cytosine-rich sequences function as independent transcriptional control elements in vitro.
1984,
Pubmed
Potter,
Eucaryotic transposable genetic elements with inverted terminal repeats.
1980,
Pubmed
Potter,
DNA sequence of a foldback transposable element in Drosophila.
1982,
Pubmed
Queen,
Three segments from the monkey genome that hybridize to simian virus 40 have common structural elements.
1981,
Pubmed
Rigby,
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.
1977,
Pubmed
Roberts,
Comparison of sea urchin and human mtDNA: evolutionary rearrangement.
1983,
Pubmed
,
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Rosenthal,
BK viral enhancer element and a human cellular homolog.
1983,
Pubmed
Rosenzweig,
Sequence of the C. elegans transposable element Tc1.
1983,
Pubmed
Saffer,
Transcription from SV 40-like monkey DNA sequences.
1984,
Pubmed
Scheller,
Repetitive sequences of the sea urchin genome. II. Subfamily structure and evolutionary conservation.
1981,
Pubmed
,
Echinobase
Seif,
The genome of human papovavirus BKV.
1979,
Pubmed
Southern,
Detection of specific sequences among DNA fragments separated by gel electrophoresis.
1975,
Pubmed
Syvanen,
The evolutionary implications of mobile genetic elements.
1984,
Pubmed
Truett,
Unusual structure of the FB family of transposable elements in Drosophila.
1981,
Pubmed
Weiher,
Multiple point mutations affecting the simian virus 40 enhancer.
1983,
Pubmed
Zuker,
Dictyostelium transposable element DIRS-1 has 350-base-pair inverted terminal repeats that contain a heat shock promoter.
1984,
Pubmed
