Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-32361
Cell Differ 1986 Jun 01;184:257-62. doi: 10.1016/0045-6039(86)90057-6.
Show Gene links Show Anatomy links

Carbonic anhydrase activity in developing sea urchin embryos with special reference to calcification of spicules.

Mitsunaga K , Akasaka K , Shimada H , Fujino Y , Yasumasu I , Numanoi H .


Abstract
Eggs and embryos of the sea urchins Anthocidaris crassispina and Hemicentrotus pulcherrimus did not exhibit significant changes in carbonic anhydrase activity during early development. Acetazolamide inhibited enzyme activity in homogenates of embryos and inhibited the formation of calcified spicules in a culture of micromeres at concentrations between 40 and 100 microM. Acetazolamide allowed intact embryos to develop to quasi-normal plutei but inhibited calcium deposition in the spicules. It is suggested that carbonic anhydrase contributes to CaCO3 deposition in the spicule.

PubMed ID: 3087630
Article link: Cell Differ


Genes referenced: LOC100887844 LOC577690