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Antimicrob Agents Chemother
2022 Dec 20;6612:e0083922. doi: 10.1128/aac.00839-22.
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Characterization of a Carbapenem-Resistant BKC-1-Producing Clinical Isolate Belonging to the Pseudomonas putida Group from Brazil.
Alberto-Lei F
,
Nodari CS
,
Streling AP
,
Bessa-Neto FO
,
Siqueira AV
,
Cayô R
,
Gales AC
.
Abstract
Since its first report, the class A Brazilian Klebsiella carbapenemase (BKC) has been detected only among Enterobacterales isolates from Brazilian hospitals. In this study, we characterized a multidrug-resistant Pseudomonas juntendi clinical isolate and identified a 43.3-kb plasmid carrying blaBKC-1 and a class 1 integron (In1996) containing the arr-2, qnrVC1, dfrA21, and aac(6')-Ib' gene cassettes. Our results confirm the ability of Pseudomonas putida group isolates to acquire antimicrobial resistance determinants and further act as resistance reservoirs.
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