ECB-ART-40009
Science
2006 Nov 10;3145801:941-52. doi: 10.1126/science.1133609.
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The genome of the sea urchin Strongylocentrotus purpuratus.
Sea Urchin Genome Sequencing Consortium
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Sodergren E
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Weinstock GM
,
Davidson EH
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Cameron RA
,
Gibbs RA
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Angerer RC
,
Angerer LM
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Arnone MI
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Burgess DR
,
Burke RD
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Coffman JA
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Dean M
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Elphick MR
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Ettensohn CA
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Foltz KR
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Hamdoun A
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Hynes RO
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Klein WH
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Marzluff W
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McClay DR
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Morris RL
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Mushegian A
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Rast JP
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Smith LC
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Thorndyke MC
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Vacquier VD
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Wessel GM
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Wray G
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Zhang L
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Elsik CG
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Ermolaeva O
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Hlavina W
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Hofmann G
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Kitts P
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Landrum MJ
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Mackey AJ
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Maglott D
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Panopoulou G
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Poustka AJ
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Pruitt K
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Sapojnikov V
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Song X
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Souvorov A
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Solovyev V
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Wei Z
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Whittaker CA
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Worley K
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Durbin KJ
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Shen Y
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Fedrigo O
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Garfield D
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Haygood R
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Primus A
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Satija R
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Severson T
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Gonzalez-Garay ML
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Jackson AR
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Milosavljevic A
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Tong M
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Killian CE
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Livingston BT
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Wilt FH
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Adams N
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Bellé R
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Carbonneau S
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Cheung R
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Cormier P
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Cosson B
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Croce J
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Fernandez-Guerra A
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Genevière AM
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Goel M
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Kelkar H
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Morales J
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Mulner-Lorillon O
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Robertson AJ
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Goldstone JV
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Cole B
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Epel D
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Gold B
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Hahn ME
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Howard-Ashby M
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Scally M
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Stegeman JJ
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Allgood EL
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Cool J
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Judkins KM
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McCafferty SS
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Musante AM
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Obar RA
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Rawson AP
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Rossetti BJ
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Gibbons IR
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Hoffman MP
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Leone A
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Istrail S
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Materna SC
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Samanta MP
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Stolc V
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Tongprasit W
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Tu Q
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Bergeron KF
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Brandhorst BP
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Whittle J
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Berney K
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Bottjer DJ
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Calestani C
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Peterson K
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Chow E
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Yuan QA
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Elhaik E
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Graur D
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Reese JT
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Bosdet I
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Heesun S
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Marra MA
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Schein J
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Anderson MK
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Brockton V
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Buckley KM
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Cohen AH
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Fugmann SD
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Hibino T
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Loza-Coll M
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Majeske AJ
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Messier C
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Nair SV
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Pancer Z
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Terwilliger DP
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Agca C
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Arboleda E
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Chen N
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Churcher AM
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Hallböök F
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Humphrey GW
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Idris MM
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Kiyama T
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Liang S
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Mellott D
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Mu X
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Murray G
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Olinski RP
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Raible F
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Rowe M
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Taylor JS
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Tessmar-Raible K
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Wang D
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Wilson KH
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Yaguchi S
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Gaasterland T
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Galindo BE
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Gunaratne HJ
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Juliano C
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Kinukawa M
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Moy GW
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Neill AT
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Nomura M
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Raisch M
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Reade A
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Roux MM
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Song JL
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Su YH
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Townley IK
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Voronina E
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Wong JL
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Amore G
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Branno M
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Brown ER
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Cavalieri V
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Duboc V
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Duloquin L
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Flytzanis C
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Gache C
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Lapraz F
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Lepage T
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Locascio A
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Martinez P
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Matassi G
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Matranga V
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Range R
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Rizzo F
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Röttinger E
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Beane W
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Bradham C
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Byrum C
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Glenn T
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Hussain S
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Manning G
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Miranda E
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Thomason R
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Walton K
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Wikramanayke A
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Wu SY
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Xu R
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Brown CT
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Chen L
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Gray RF
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Lee PY
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Nam J
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Oliveri P
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Smith J
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Muzny D
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Bell S
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Chacko J
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Cree A
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Curry S
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Davis C
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Dinh H
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Dugan-Rocha S
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Fowler J
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Gill R
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Hamilton C
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Hernandez J
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Hines S
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Hume J
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Jackson L
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Jolivet A
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Kovar C
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Lee S
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Lewis L
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Miner G
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Morgan M
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Nazareth LV
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Okwuonu G
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Parker D
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Pu LL
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Thorn R
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Wright R
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???displayArticle.abstract???
We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.
???displayArticle.pubmedLink??? 17095691
???displayArticle.pmcLink??? PMC3159423
???displayArticle.link??? Science
???displayArticle.grants??? [+]
P42 ES007381 NIEHS NIH HHS , R37-HD12896 NICHD NIH HHS , GM058231 NIGMS NIH HHS , P01 HD037105 NICHD NIH HHS , 2P42 ESO7381 PHS HHS , F32 HD047136 NICHD NIH HHS , F32 HD047136-03 NICHD NIH HHS , GM61005 NIGMS NIH HHS , R01 ES006272 NIEHS NIH HHS , T32 GM007601 NIGMS NIH HHS , P01 HD039948 NICHD NIH HHS , S19916 Biotechnology and Biological Sciences Research Council , P40 OD010959 NIH HHS , R01 GM061005 NIGMS NIH HHS , P30 CA014051 NCI NIH HHS , R43 CA093106 NCI NIH HHS , R01 GM070840 NIGMS NIH HHS , GM61464 NIGMS NIH HHS , U54 HG003273 NHGRI NIH HHS , P30-CA14051 NCI NIH HHS , F32 ES012794 NIEHS NIH HHS , EY11930 NEI NIH HHS , R01 HD028152 NICHD NIH HHS , R01 EY011930 NEI NIH HHS , F32 ESO12794 PHS HHS , RR-15044 NCRR NIH HHS , R01 HD014483 NICHD NIH HHS , R01 GM058231 NIGMS NIH HHS , HD14483 NICHD NIH HHS , HD039948 NICHD NIH HHS , HD66219 NICHD NIH HHS , F32-HD47136 NICHD NIH HHS , R44 CA093106 NCI NIH HHS , R01ES006272 NIEHS NIH HHS , 5 U54 HG003273 NHGRI NIH HHS , F32 HD047136-02 NICHD NIH HHS , P40 RR015044 NCRR NIH HHS , GM070840 NIGMS NIH HHS , HD-37105 NICHD NIH HHS , R01 ES006272-13 NIEHS NIH HHS , R01 HD066219 NICHD NIH HHS , R01 GM061464 NIGMS NIH HHS , R01 DC020052 NIDCD NIH HHS
Genes referenced: LOC100887844
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