ECB-ART-37284
Toxicon
1999 Nov 01;3711:1639-43. doi: 10.1016/s0041-0101(99)00094-x.
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A toxic extract from sea urchin (T. pileolus) inhibits 45Ca2+ uptake in P2 fraction from chick brain under physiological ionic conditions.
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An acidic toxic extract from the sea urchin T. pileolus inhibited time-dependent 45Ca2+ uptake in chick P2 fraction (IC50 about 10 ng/ml). This toxic extract is susceptible to trypsin. The inhibitory effect probably relate to Na+/Ca2+ exchanger.
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Genes referenced: LOC100887844