ECB-ART-41111Int J Dev Biol 2009 Jan 01;535-6:707-16. doi: 10.1387/ijdb.072495ip.
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Genomic control of patterning.
The development of multicellular organisms involves the partitioning of the organism into territories of cells of specific structure and function. The information for spatial patterning processes is directly encoded in the genome. The genome determines its own usage depending on stage and position, by means of interactions that constitute gene regulatory networks (GRNs). The GRN driving endomesoderm development in sea urchin embryos illustrates different regulatory strategies by which developmental programs are initiated, orchestrated, stabilized or excluded to define the pattern of specified territories in the developing embryo.
PubMed ID: 19378258
PMC ID: PMC3967875
Article link: Int J Dev Biol
Genes referenced: LOC100887844 LOC575170
References [+] :
Arenas-Mena, Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo. 2006, Pubmed, Echinobase