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Structural and functional characterization of mouse U7 small nuclear RNA active in 3'' processing of histone pre-mRNA.
Soldati D
,
Schümperli D
.
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Oligonucleotides derived from the spacer element of the histone RNA 3'' processing signal were used to characterize mouse U7 small nuclear RNA (snRNA), i.e., the snRNA component active in 3'' processing of histone pre-mRNA. Under RNase H conditions, such oligonucleotides inhibited the processing reaction, indicating the formation of a DNA-RNA hybrid with a functional ribonucleoprotein component. Moreover, these oligonucleotides hybridized to a single nuclear RNA species of approximately 65 nucleotides. The sequence of this RNA was determined by primer extension experiments and was found to bear several structural similarities with sea urchin U7 snRNA. The comparison of mouse and sea urchin U7 snRNA structures yields some further insight into the mechanism of histone RNA 3'' processing.
Billeter,
Cloning of DNA corresponding to four different measles virus genomic regions.
1984, Pubmed
Billeter,
Cloning of DNA corresponding to four different measles virus genomic regions.
1984,
Pubmed
Birchmeier,
The terminal RNA stem-loop structure and 80 bp of spacer DNA are required for the formation of 3' termini of sea urchin H2A mRNA.
1983,
Pubmed
,
Echinobase
Birchmeier,
3' editing of mRNAs: sequence requirements and involvement of a 60-nucleotide RNA in maturation of histone mRNA precursors.
1984,
Pubmed
,
Echinobase
Birnstiel,
Transcription termination and 3' processing: the end is in site!
1985,
Pubmed
Coles,
An H1 histone gene-specific 5' element and evolution of H1 and H5 genes.
1985,
Pubmed
D'Andrea,
Vertebrate histone genes: nucleotide sequence of a chicken H2A gene and regulatory flanking sequences.
1981,
Pubmed
,
Echinobase
England,
3'-terminal labelling of RNA with T4 RNA ligase.
1978,
Pubmed
Georgiev,
The conserved CAAGAAAGA spacer sequence is an essential element for the formation of 3' termini of the sea urchin H3 histone mRNA by RNA processing.
1985,
Pubmed
,
Echinobase
Gick,
Generation of histone mRNA 3' ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction.
1986,
Pubmed
,
Echinobase
Gick,
Heat-labile regulatory factor is required for 3' processing of histone precursor mRNAs.
1987,
Pubmed
,
Echinobase
Gilmartin,
Functional analysis of the sea urchin U7 small nuclear RNA.
1988,
Pubmed
,
Echinobase
Harvey,
Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5' element.
1982,
Pubmed
,
Echinobase
Heintz,
The structure of the human histone genes: clustered but not tandemly repeated.
1981,
Pubmed
Hentschel,
The organization and expression of histone gene families.
1981,
Pubmed
Krainer,
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro.
1985,
Pubmed
Krieg,
Formation of the 3' end of histone mRNA by post-transcriptional processing.
1984,
Pubmed
,
Echinobase
Krämer,
The 5' terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors.
1984,
Pubmed
Lüscher,
RNA 3' processing regulates histone mRNA levels in a mammalian cell cycle mutant. A processing factor becomes limiting in G1-arrested cells.
1987,
Pubmed
Maxam,
Sequencing end-labeled DNA with base-specific chemical cleavages.
1980,
Pubmed
Reddy,
Primary and secondary structure of U8 small nuclear RNA.
1985,
Pubmed
Schaufele,
Compensatory mutations suggest that base-pairing with a small nuclear RNA is required to form the 3' end of H3 messenger RNA.
1986,
Pubmed
,
Echinobase
Seiler-Tuyns,
Structure and expression in L-cells of a cloned H4 histone gene of the mouse.
1981,
Pubmed
Sierra,
Structure and in vitro transcription of a human H4 histone gene.
1983,
Pubmed
Sippel,
Purification and characterization of adenosine triphosphate: ribonucleic acid adenyltransferase from Escherichia coli.
1973,
Pubmed
Sittman,
Structure of a cluster of mouse histone genes.
1983,
Pubmed
Stauber,
A signal regulating mouse histone H4 mRNA levels in a mammalian cell cycle mutant and sequences controlling RNA 3' processing are both contained within the same 80-bp fragment.
1986,
Pubmed
Strub,
The cDNA sequences of the sea urchin U7 small nuclear RNA suggest specific contacts between histone mRNA precursor and U7 RNA during RNA processing.
1984,
Pubmed
,
Echinobase
Strub,
Genetic complementation in the Xenopus oocyte: co-expression of sea urchin histone and U7 RNAs restores 3' processing of H3 pre-mRNA in the oocyte.
1986,
Pubmed
,
Echinobase
Stunnenberg,
Bioassay for components regulating eukaryotic gene expression: a chromosomal factor involved in the generation of histone mRNA 3' termini.
1982,
Pubmed
,
Echinobase
Sugarman,
Genomic organization, DNA sequence, and expression of chicken embryonic histone genes.
1983,
Pubmed
,
Echinobase
Taylor,
Sequences of four mouse histone H3 genes: implications for evolution of mouse histone genes.
1986,
Pubmed
Turner,
H3 and H4 histone cDNA sequences from Xenopus: a sequence comparison of H4 genes.
1982,
Pubmed
Zhong,
The primary structure and expression of four cloned human histone genes.
1983,
Pubmed
