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ECB-GENEPAGE-23049519
Gene Symbol h2a
![]() Symbol Status
![]() Gene Name histone h2A
![]() Name Status
![]() Synonyms:
EhH2a
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EhH2a_1
,
EhH2a_10
,
EhH2a_11
,
EhH2a_12
,
EhH2a_13
[+]
(
Gene Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the Protein Function
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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central ro...[+]
Interactants:
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Diseases: External Links:
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