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Echinobase

Summary ExpressionExpr. Gene Literature (7)Lit. (7) GO Terms (62)GO (62) Nucleotides (16)Nucl. (16) Proteins (12)Prot. (12) Interactants (20)Interact. (20) Wiki
ECB-GENEPAGE-23194288
???displayGene.symbol??? :
 hmgcr
Symbol Status : Curated


???displayGene.name???: 
3-hydroxy-3-methylglutaryl-CoA reductase
Name Status : Curated


???displayGene.synonyms???
3-hydroxy-3-methylglutaryl-coenzyme A reductase , HMG-CoA reductase , LOC110986789 , Sp-Hmgcr , Sp-Hmgcr_1 , SPU_005963 [+] ( Nomenclature history )

???displayGene.geneFunction???
This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.

AI Protein Function :
hmgcr encodes a membrane‑bound enzyme that catalyzes the NADPH‑dependent reduction of HMG‑CoA to mevalonate, the rate‑limiting step of the mevalonate pathway for isoprenoid and sterol biosynthesis; the...[+]


InterPro :
HMG CoA Rdtase NAD(P)-bd sf, SSD, HMG CoA Rdtase N, HMG CoA Rdtase sub-bd dom sf, [+]

???displayGene.geneInteractants???
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